Materials and methods: A total of 163 gout patients and 187 normal controls from Minnan
were enrolled in this case-control study. SNPs (rs1165205, rs3733591, rs6855911 …

Background Serum uric acid (UA) levels have recently been shown to be genetically
influenced by common polymorphisms in the GLUT9 gene in two genome-wide association …

We have recently identified four novel genomic loci influencing gout susceptibility at the
genome-wide significance level (P< 5.0× 10–8) via genome-wide association study (GWAS) …

Background Gout is a common type of arthritis that is characterized by hyperuricemia, tophi
and joint inflammation. Genetic variations in the ABCG2 gene have been reported to …

Gout is one of the most kinds of common inflammatory arthritis as a consequence of
hyperuricemia. Alpha-protein kinase 1 (ALPK1) gene locates in a gout-susceptibility locus …

Objective. Gout is characterized by recurrent attacks of arthritis with hyperuricaemia and
urate crystal-induced inflammation. Although urate transporters are known as risk factors …

Objectives Genome-wide meta-analyses of clinically defined gout were performed to identify
subtype-specific susceptibility loci. Evaluation using selection pressure analysis with these …

The aim of the study was to examine whether SLC22A12 gene mutations might be
influenced in primary gout disease. We included 32 patients with diagnosis of primary gout …

Objective. Recently, genetic analyses indicated the association between gout and cGMP-
dependent protein kinase 2 (cGKII/PRKG2) gene in a Fukien-Taiwanese heritage …

Background Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple
single-nucleotide polymorphisms (SNPs) have been identified as associated with both …