We applied a family-based association approach to investigate the role of the DYX1C1 gene
on chromosome 15q as a candidate gene for developmental dyslexia (DD) to 158 families …

Dyslexia is a common heterogeneous disorder with a significant genetic component.
Multiple studies have replicated the evidence for linkage between variously defined …

A substantial genetic contribution in the etiology of developmental dyslexia (DD) has been
well documented with independent groups reporting a susceptibility locus on chromosome …

Background Dyslexia is a learning disability that is characterized by difficulties in the
acquisition of reading and spelling skills independent of intelligence, motivation or …

Developmental dyslexia, or reading disability, is a multigenic complex disease for which at
least five loci, ie DYX1–3 and DYX5–6, have been clearly identified from the human …

Reading disabilities (RD) have a significant genetic basis and have shown linkage to
multiple regions including chromosome 15q. Dyslexia susceptibility 1 candidate gene 1 …

Objective Dyslexia-susceptibility-1-candidate-1 (DYX1C1) was the first gene associated with
dyslexia. Since the original report of 2003, eight replication attempts have been published …

The status of DYX1C1 (C15q21. 3) as a susceptibility gene for dyslexia is unclear. We report
the association of this gene with reading and spelling ability in a sample of adolescent twins …

Abstract Recently, DYX1C1, a candidate gene for developmental dyslexia, encoding a
nuclear tetratricopepetide repeat domain protein dynamically regulated in brain, has been …

Dyslexia is one of the most common childhood disorders with a prevalence of around 5–
10% in school-age children. Although an important genetic component is known to have a …