Utilizing targeted therapies capable of reducing cancer metastasis, targeting chemoresistant
and self-renewing cancer stem cells, and augmenting the efficacy of systemic …

A blueprint for the ideal anticancer molecule would include most of the properties of nitric
oxide (NO•), but the ability to exploit these characteristics in a therapeutic setting requires a …

The role of nitric oxide (NO•) as a mediator of cancer phenotype has led researchers to
investigate strategies for manipulating in vivo production and exogenous delivery of this …

Nitric oxide (NO) is a signaling molecule with pleiotropic physiological roles in normal cells
and pathophysiological roles in cancer. NO synthetase expression and NO synthesis are …

Nitric oxide (NO) is a short-lived, pleiotropic molecule that affects numerous critical functions
in the body. Presently, there are markedly conflicting findings in the literature regarding NO …

Purpose The diatomic radical nitric oxide (NO) has been the cause of intense debate with
implication in carcinogenesis, tumour progression, invasion, angiogenesis and modulation …

Tumor resistance to cytotoxic therapeutics coupled with dose-limiting toxicity is a serious
hurdle in the field of medical oncology. In the face of this obstacle, nitric oxide has emerged …

Significance: Cancer is a complex disease, which not only involves the tumor but its
microenvironment comprising different immune cells as well. Nitric oxide (NO) plays specific …

Nitric oxide (NO) is a ubiquitous gas with free radical groups that is soluble in water, and
which is involved in numerous physiological functions including inflammatory and immune …

Much research over the past two decades has focussed on understanding the complex
interactions of nitric oxide (NO) in both physiological and pathological processes. As with …