Low level nitric oxide (NO) produced by inducible NO synthase (iNOS) in many malignant
tumors is known to play a key role in the survival and proliferation of tumor cells. NO can …

The mechanistic roles of nitric oxide (NO) during cancer progression have been important
considerations since its discovery as an endogenously generated free radical. Nonetheless …

Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical
functions in the body. There are markedly conflicting findings in the literature regarding the …

Nitric oxide (NO) is a pleiotropic molecule critical to a number of physiological and
pathological processes. The last decade has witnessed major advances in dissecting NO …

In recent years, there has been an increasing interest in understanding the mysterious
functions of nitric oxide (NO) and how this pleiotropic signaling molecule contributes to …

Nitric Oxide (NO) is a highly diffusible, ubiquitous signaling molecule and a free radical that
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …

Nitric oxide (NO) and nitric oxide synthases are ubiquitous in malignant tumours and are
known to exert both pro-and anti-tumour effects. We summarize our current understanding of …

Nitric oxide is a key second messenger in most tissues, where it is generated at low
concentrations, predominantly by the catalytic action of two constitutively expressed isoforms …

Despite the improved understanding of nitric oxide (NO) biology and the large amount of
preclinical experiments testing its role in cancer development and progression, it is still …

Purpose: Aberrant expression of inflammatory molecules, such as inducible nitric oxide (NO)
synthase (iNOS), has been linked to cancer, suggesting that their inhibition is a rational …