The increasing understanding of the role of nitric oxide (NO) in cancer biology has
generated significant progress in the use of NO donor-based therapy to fight cancer. These …

Nitric oxide (NO) is a ubiquitous molecule with a myriad of physiological and
pathophysiological roles. It has numerous direct and indirect effects on tumour vasculature …

The role of nitric oxide (NO) in tumor biology remains controversial and poorly understood.
While a few reports indicate that the presence of NO in tumor cells or their micro …

Aims: Our previous studies have shown that nitric oxide (NO) plays an important role in
increasing the invasion and proliferation of human melanoma cells, suggesting that …

Altered metabolic phenotype has been recognized as a hallmark of tumor cells for many
years, but this aspect of the cancer phenotype has come into greater focus in recent years …

Despite recognition of the malignant potential of human melanomas, the mechanisms
responsible for the pathobiological characteristics contributing to tumor growth, vascular …

The role of nitric oxide (NO) in cancer development has become a very active research area.
This review presents an overview of many studies that implicate an important role of NO in …

Background Nitric oxide-releasing drugs are used for cardiovascular diseases; however,
their effects on the tumor immune microenvironment are less clear. Therefore, this study …

Nitric oxide (NO) in nanomolar (nmol/L) concentrations is consistently detected in tumor
microenvironment and has been found to promote tumorigenesis. The mechanism by which …

The role of nitric oxide (NO) in cancer has been controversial and is based on the levels of
NO and the responsiveness of the tumor type. It remains unclear whether NO can inhibit the …