Mechanical factors affecting nebulized albuterol aerosol particle sizes for asthma drug delivery
NK Itoga, CK Kinoshita, SM Masutani… - The American Journal of …, 2014 - Elsevier
Background Nebulized particles must have diameters between 1 to 5 μ m (optimal particle
size range [OPSR]) to be deposited in the lower respiratory tract. The purpose of this study is …
size range [OPSR]) to be deposited in the lower respiratory tract. The purpose of this study is …
Factors Affecting Nebulized Albuterol Aerosol Particle Sizes
NK Itoga, CK Kinoshita, SM Masutani… - Annals of …, 2013 - annemergmed.com
Study Objectives Albuterol and other asthma medications are commonly delivered to the
lungs via nebulization. Particle sizes from the nebulization process should ideally be in the …
lungs via nebulization. Particle sizes from the nebulization process should ideally be in the …
Continuous nebulization therapy for asthma with aerosols of β2 agonists
OG Raabe, TM Wong, GB Wong, JW Roxburgh… - Annals of Allergy …, 1998 - Elsevier
BACKGROUND: Various studies have demonstrated the benefits of continuous nebulization
therapy for delivering aerosols of the beta2 agonists such as terbutaline sulfate or albuterol …
therapy for delivering aerosols of the beta2 agonists such as terbutaline sulfate or albuterol …
Four hours of continuous albuterol nebulization
A Berlinski, JC Waldrep - Chest, 1998 - Elsevier
Background and objectives: Continuous albuterol nebulization (CAN) is a therapeutic
modality available to treat status asthmaticus. Currently, CAN may be administered using a …
modality available to treat status asthmaticus. Currently, CAN may be administered using a …
In-vitro comparison of 4 large-volume nebulizers in 8 hours of continuous nebulization
A Berlinski, JR Willis, T Leisenring - Respiratory Care, 2010 - rc.rcjournal.com
BACKGROUND: Continuous albuterol nebulization has become the standard of care for
patients with status asthmaticus. Predictable albuterol delivery is paramount for effective …
patients with status asthmaticus. Predictable albuterol delivery is paramount for effective …
Medication nebulizer performance: effects of diluent volume, nebulizer flow, and nebulizer brand
D Hess, D Fisher, P Williams, S Pooler, RM Kacmarek - Chest, 1996 - Elsevier
Background Medication nebulizers are commonly used to delivery aerosolized medications
to patients with respiratory disease. We evaluated output and respirable aerosol available to …
to patients with respiratory disease. We evaluated output and respirable aerosol available to …
Characterization of aerosol output from various nebulizer/compressor combinations
C Reisner, RK Katial, BB Bartelson, A Buchmeir… - Annals of Allergy …, 2001 - Elsevier
OBJECTIVES: Different commercially available nebulizers and compressors are available.
However, the optimal combination for drug delivery is unknown. METHODS: Flow rates of …
However, the optimal combination for drug delivery is unknown. METHODS: Flow rates of …
Effects of bronchodilator particle size in asthmatic patients using monodisperse aerosols
OS Usmani, MF Biddiscombe… - Journal of Applied …, 2003 - journals.physiology.org
Aerosol particle size influences airway drug deposition. Current inhaler devices are
inefficient, delivering a heterodisperse distribution of drug particle sizes where, at best, 20 …
inefficient, delivering a heterodisperse distribution of drug particle sizes where, at best, 20 …
Comparison of volume output from two different continuous nebulizer systems
C Reisner, J Lee, A Kotch, G Dworkin - Annals of Allergy, Asthma & …, 1996 - Elsevier
BACKGROUND: Continuous nebulization is a safe and practical method of administration of
beta2-adrenergic agonists during acute asthma. There are essentially 2 types of continuous …
beta2-adrenergic agonists during acute asthma. There are essentially 2 types of continuous …
Effects of Environmental and Mechanical Variations on Particle Size Distribution of Albuterol HFA Inhalers
KL Rhodes, I Nagamine, SM Masutani… - Respiratory …, 2021 - rc.rcjournal.com
BACKGROUND: The purpose of this study was to evaluate how factors (ambient
temperature, shaking the inhaler before use, suspension of the inhaler in water, and the …
temperature, shaking the inhaler before use, suspension of the inhaler in water, and the …