There has been a limited number of systematic reviews conducted to summarize the
overview of the relationship between DNA methylation and depression, and to critically …

As one of the most common psychiatric disorders, depression has been a major public
health problem. Growing evidence suggests that epigenetic modification is essential in …

Background Growing evidence suggests that epigenetic modification is vital in biological
processes of depression. Findings from studies exploring the associations between DNA …

Major depressive disorder (MDD) is the leading cause of disability worldwide and is
associated with high rates of suicide and medical comorbidities. Current antidepressant …

Antidepressant medications are the most common treatment for major depression and
related disorders. Pharmacogenetic studies have demonstrated that response to these …

Depression is one of the most common psychiatric disorders affecting public health. Studies
over the past years suggest that the methylations of some specific genes such as BDNF …

Importance Depressive disorders arise from a combination of genetic and environmental risk
factors. Epigenetic disruption provides a plausible mechanism through which gene …

Despite that burnout presents a serious burden for modern society, there are no diagnostic
criteria. Additional difficulty is the differential diagnosis with depression. Consequently, there …

Background: Several broad lines of evidence support the involvement of epigenetic
processes in neurodevelopment and psychiatric disorders. Epigenetic disruption also …

Epigenetic mechanisms such as DNA methylation (DNAm) have been associated with stress
responses and increased vulnerability to depression. Abnormal DNAm is observed in …