The oxygen therapy is a universal treatment in the hospital setting, especially in the critical
care units. The purpose of this therapy is to avoid hypoxemia and to ensure an adequate …

Rationale: Mechanically ventilated patients in the intensive care unit (ICU) are often
managed to maximize oxygenation, yet hyperoxemia may be deleterious to some. Little is …

Background: Current clinical practice guidelines promote a goal-directed approach for
oxygen delivery with respect to SpO2 objectives. We evaluated the efficiency of a strategy …

Objective: To search for a threshold of pulmonary oxygen toxicity in patients with acute
respiratory failure. Design: Retrospective study over a 10-year period. Setting: Three …

Background Oxygen therapy is a common treatment in the intensive care unit (ICU) with both
potentially desirable and undesirable long‐term effects. This systematic review aimed to …

Background In mechanically ventilated (MV) cardiac arrest (CA) survivors admitted to the
intensive care unit (ICU) avoidance of hypoxia is considered crucial. However, avoidance of …

Background Despite oxygen being the commonest drug administered to critically ill patients
we do not know which oxygen saturation (SpO2) target results in optimal survival outcomes …

Purpose This study described the acute hypoxemic respiratory failure (AHRF) population
and identified potential modifiable markers of outcome. Methods A prospective, multicenter …

Objective Oxygen has been used liberally in ICUs for a long time to prevent hypoxia in ICU-
patients. Current evidence suggests that paO 2> 300 mmHg should be avoided, it remains …

Background Liberal oxygen supplementation is often used in acute illness but has, in some
studies, been associated with harm. Research Question The goal of this study was to assess …