Hyperoxia, or excess oxygen supplementation, prevails in the intensive care unit (ICU)
without a beneficial effect and, in some instances, may cause harm. Recent interest and …

Purpose Sepsis is a common reason for intensive care unit (ICU) admission and mortality in
ICU patients. Despite increasing interest in treatment strategies limiting oxygen exposure in …

Background The role of conservative versus liberal oxygen therapy for acutely ill patients
remains controversial. Objective To systematically review the available evidence regarding …

Hypoxemia is a frequent phenomenon in patients with acute lung injury (ALI) from various
origins related or unrelated to pulmonary diseases. One of the most effective therapies is the …

Objectives: Conservative oxygen therapy is aimed at the prevention of harm by iatrogenic
hyperoxia while preserving adequate tissue oxygenation. Our aim was to study the …

From 'elixir of the life'to the first cause of aging and death, the history of oxygen in modern
science and medicine is a fascinating example of controversial hypotheses, uncertain …

Background Intensive care unit (ICU) patients face a significant rise in mortality rates due to
acute hypoxemic respiratory failure (AHRF). The diagnosis of AHRF is based on the PF ratio …

Background Acute respiratory distress syndrome (ARDS) is characterized by a
noncardiogenic pulmonary edema with bilateral chest X-ray opacities and reduction in lung …

Oxygen is both lifesaving and toxic. Appropriate use of oxygen aims to provide a balance
between the two effects. Although local oxygen toxicity to the lung is well accepted, recent …

Introduction Some clinicians take an aggressive approach to supplemental oxygen therapy
to avoid the dangers of hypoxaemia but many patients, especially those with COPD, are at …