Insulin, insulin resistance, obesity, and cancer
EJ Gallagher, D LeRoith - Current diabetes reports, 2010 - Springer
Epidemiologic studies have proposed a link between obesity, type 2 diabetes, and cancer.
The pathophysiologic mechanisms involved in the development of type 2 diabetes, namely …
The pathophysiologic mechanisms involved in the development of type 2 diabetes, namely …
Obesity, type 2 diabetes, and cancer: the insulin and IGF connection
DH Cohen, D LeRoith - Endocrine-related cancer, 2012 - erc.bioscientifica.com
Epidemiological studies suggest a positive association between obesity and type 2 diabetes
mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance …
mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance …
Diabetes and cancer: A critical appraisal of the pathogenetic and therapeutic links
V Gristina, MG Cupri, M Torchio… - Biomedical …, 2015 - spandidos-publications.com
Diabetes and cancer represent two common, multifactorial, chronic and potentially fatal
diseases, not infrequently co‑diagnosed in the same patient. Epidemiological data …
diseases, not infrequently co‑diagnosed in the same patient. Epidemiological data …
Diabetes and cancer: two diseases with obesity as a common risk factor
SK Garg, H Maurer, K Reed… - Diabetes, Obesity and …, 2014 - Wiley Online Library
There is a growing body of evidence to support a connection between diabetes
(predominantly type 2), obesity and cancer. Multiple meta‐analyses of epidemiological data …
(predominantly type 2), obesity and cancer. Multiple meta‐analyses of epidemiological data …
Obesity and type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence
D LeRoith, R Novosyadlyy, EJ Gallagher… - Experimental and …, 2008 - thieme-connect.com
Both obesity and Type 2 diabetes are independently associated with an increased risk of
developing cancer and an increased mortality. The etiology is yet to be determined but …
developing cancer and an increased mortality. The etiology is yet to be determined but …
Insulin Resistance: The Increased Risk of Cancers
L Szablewski - Current Oncology, 2024 - mdpi.com
Insulin resistance, also known as impaired insulin sensitivity, is the result of a decreased
reaction of insulin signaling to blood glucose levels. This state is observed when muscle …
reaction of insulin signaling to blood glucose levels. This state is observed when muscle …
The relation of type 2 diabetes and cancer
HD Strickler, J Wylie-Rosett, T Rohan… - Diabetes technology …, 2001 - liebertpub.com
Increasing evidence indicates that individuals with type 2 diabetes (diabetes) are at elevated
risk for several common human malignancies, including cancers of the colon, breast …
risk for several common human malignancies, including cancers of the colon, breast …
Obesity, type 2 diabetes, and cancer risk
T Scully, A Ettela, D LeRoith, EJ Gallagher - Frontiers in oncology, 2021 - frontiersin.org
Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …
The pathway from diabetes and obesity to cancer, on the route to targeted therapy
EJ Gallagher, Y Fierz, RD Ferguson, D LeRoith - Endocrine Practice, 2010 - Elsevier
Objective To review the epidemiologic studies that describe the relationships among
diabetes, obesity, and cancer; animal studies that have helped to decipher the mechanisms …
diabetes, obesity, and cancer; animal studies that have helped to decipher the mechanisms …
Diabetes, antihyperglycemic medications and cancer risk: smoke or fire?
EJ Gallagher, D LeRoith - Current Opinion in Endocrinology …, 2013 - journals.lww.com
Objective The aim of this review article is to discuss the epidemiological links between
diabetes and cancer; the potential biological mechanisms linking diabetes, obesity and …
diabetes and cancer; the potential biological mechanisms linking diabetes, obesity and …