Locomotor exercise enhances supraspinal control of lower-urinary-tract activity to improve micturition function after contusive spinal-cord injury

L Deng, T Sui, DV Wang, S Hou, X Cao, K Peng, Z Xu… - Cells, 2022 - mdpi.com
The recovery of lower-urinary-tract activity is a top priority for patients with spinal-cord injury.
Historically, locomotor training improved micturition function in both patients with spinal cord …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

Improvements in bladder function following activity-based recovery training with epidural stimulation after chronic spinal cord injury

AN Herrity, SC Aslan, B Ugiliweneza… - Frontiers in systems …, 2021 - frontiersin.org
Spinal cord injury (SCI) results in profound neurologic impairment with widespread deficits
in sensorimotor and autonomic systems. Voluntary and autonomic control of bladder …

Pharmacologic and potential biologic interventions to restore bladder function after spinal cord injury

N Yoshimura, CP Smith, MB Chancellor… - Current opinion in …, 2000 - journals.lww.com
Spinal cord injury disrupts voluntary control of voiding and the normal reflex pathways that
coordinate bladder and urethral sphincter function. The present review addresses studies in …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

The dysfunctional bladder following spinal cord injury: From concept to clinic

DC Baptiste, M Elkelini, M Hassouna… - Current Bladder …, 2009 - Springer
Lower urinary tract dysfunction is a common problem among individuals with spinal cord
injury (SCI) that results from a disruption of coordinated control among the brain, spinal cord …

Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …

Chronic chemogenetic inhibition of TRPV1 bladder afferent promotes micturition recovery post SCI

L Ma, C Zhu, YF Wei, JY Zhou, M Chen, X Zhang… - Experimental …, 2024 - Elsevier
Spinal cord injury often results in chronic loss of micturition control, which is featured by
bladder hyperreflexia and detrusor sphincter dyssynergia. Previous studies showed that …

Non-invasive neuromodulation of spinal cord restores lower urinary tract function after paralysis

PN Gad, E Kreydin, H Zhong, K Latack… - Frontiers in …, 2018 - frontiersin.org
It is commonly assumed that restoration of locomotion is the ultimate goal after spinal cord
injury (SCI). However, lower urinary tract (LUT) dysfunction is universal among SCI patients …

Neuromodulation of the neural circuits controlling the lower urinary tract

PN Gad, RR Roy, H Zhong, YP Gerasimenko… - Experimental …, 2016 - Elsevier
The inability to control timely bladder emptying is one of the most serious challenges among
the many functional deficits that occur after a spinal cord injury. We previously demonstrated …