Design, synthesis, biological evaluation, and docking study of new triazole-phenylacetamide derivatives as α-glucosidase inhibitors
S Luo, W Yang, Y Huang, Z Peng, G Wang - Bioorganic Chemistry, 2023 - Elsevier
To discover potent α-glucosidase inhibitors, a class of novel triazole-phenylacetamide
derivatives (5a-5p) were designed, prepared, and tested for their α-glucosidase inhibitory …
derivatives (5a-5p) were designed, prepared, and tested for their α-glucosidase inhibitory …
Design, synthesis, in vitro, and in silico studies of novel diarylimidazole-1, 2, 3-triazole hybrids as potent α-glucosidase inhibitors
M Saeedi, M Mohammadi-Khanaposhtani… - Bioorganic & medicinal …, 2019 - Elsevier
In this work, new derivatives of diarylimidazole-1, 2, 3-triazole 7a-p were designed,
synthesized, and evaluated for their in vitro α-glucosidase inhibitory activity. All compounds …
synthesized, and evaluated for their in vitro α-glucosidase inhibitory activity. All compounds …
Novel carbazole-oxadiazole derivatives as anti-α-glucosidase and anti-α-amylase agents: Design, synthesis, molecular docking, and biological evaluation
S Luo, L Zhao, H Peng, Z Peng, G Wang - European Journal of Medicinal …, 2024 - Elsevier
To find novel inhibitors of α-glucosidase and α-amylase, a series of new carbazole-
oxadiazole derivatives (6a-6n) were prepared, and screened for their anti-α-glucosidase …
oxadiazole derivatives (6a-6n) were prepared, and screened for their anti-α-glucosidase …
Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs
Abstract α-Glucosidase is a catabolic enzyme that regulates the body's plasma glucose
levels by providing energy sources to maintain healthy functioning. 2-Amino-thiadiazole (1 …
levels by providing energy sources to maintain healthy functioning. 2-Amino-thiadiazole (1 …
Synthesis, in vitro and computational studies of novel glycosyl-1, 2, 3-1H-triazolyl methyl benzamide derivatives as potential α-glucosidase inhibitory activity
A series of novel glycosyl-1, 2, 3-1H-triazolyl methyl benzamide analogues were
synthesized by the unambiguous strategy and evaluated for α-glucosidase inhibitory activity …
synthesized by the unambiguous strategy and evaluated for α-glucosidase inhibitory activity …
New phthalimide-benzamide-1,2,3-triazole hybrids; design, synthesis, α-glucosidase inhibition assay, and docking study
SE Sadat-Ebrahimi, A Rahmani… - Medicinal Chemistry …, 2020 - Springer
A new series of phthalimide-benzamide-1, 2, 3-triazole hybrids 8a–k as α-glucosidase
inhibitors was designed and synthesized. The biological evaluation of compounds 8a–k …
inhibitors was designed and synthesized. The biological evaluation of compounds 8a–k …
Design, synthesis, molecular docking, and ADME prediction evaluation of phenyloxazole derivatives as α-glucosidase inhibitors
M Fan, W Yang, Z Peng, G Wang - Journal of Molecular Structure, 2023 - Elsevier
A class of new phenyloxazole derivatives (6a-6p) was synthesized, and their inhibitory
activities towards α-glucosidase were researched. All synthesized compounds displayed …
activities towards α-glucosidase were researched. All synthesized compounds displayed …
Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors
G Wang, Z Peng, J Wang, X Li, J Li - European journal of medicinal …, 2017 - Elsevier
A novel series of triazine-triazole derivatives 7a–7m were synthesized, characterized by 1 H
NMR and evaluated for their α-glucosidase inhibitory activity. All the synthesized …
NMR and evaluated for their α-glucosidase inhibitory activity. All the synthesized …
Design, synthesis, and biological evaluation of new indole-acrylamide-1, 2, 3-triazole derivatives as potential α-glucosidase inhibitors
SE Sadat-Ebrahimi, H Babania… - Polycyclic Aromatic …, 2022 - Taylor & Francis
In this work, new indole-acrylamide-1, 2, 3-triazole derivatives 9a–j were synthesized via
simple and efficient chemical reactions and screened for in vitro anti-α-glucosidase …
simple and efficient chemical reactions and screened for in vitro anti-α-glucosidase …
Thiazole-benzamide derivatives as α-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo evaluation
M Fan, Q Feng, W Yang, Z Peng, G Wang - Journal of Molecular Structure, 2023 - Elsevier
In this study, a series of thiazole-benzamide derivatives (6a-6o) was obtained by molecular
hybridization and screened for their inhibitory study towards the α-glucosidase activity. The …
hybridization and screened for their inhibitory study towards the α-glucosidase activity. The …
相关搜索
- α glucosidase biological evaluation
- α glucosidase molecular docking
- α glucosidase design synthesis
- α glucosidase triazine triazole
- α glucosidase inhibition assay
- α glucosidase indole acrylamide
- α glucosidase carbazole moiety
- molecular docking prediction evaluation
- biological evaluation indole acrylamide
- biological evaluation carbazole moiety
- α glucosidase prediction evaluation