Gingipain adhesin domains mediate Porphyromonas gingivalis adherence to epithelial cells

T Chen, MJ Duncan - Microbial pathogenesis, 2004 - Elsevier
Porphyromonas gingivalis, a Gram-negative oral anaerobe, interacts with epithelium lining
the gingival sulcus. Continuing our studies on the role of gingipain cysteine proteinases in P …

Porphyromonas gingivalis Gingipains and Adhesion to Epithelial Cells

T Chen, K Nakayama, L Belliveau… - Infection and …, 2001 - Am Soc Microbiol
Porphyromonas gingivalis is one of the principal organisms associated with adult
periodontitis. Bacterial surface proteins such as fimbriae and gingipain hemagglutinin …

Clathrin‐dependent entry of a gingipain adhesin peptide and Porphyromonas gingivalis into host cells

H Boisvert, MJ Duncan - Cellular microbiology, 2008 - Wiley Online Library
Porphyromonas gingivalis, a Gram‐negative oral anaerobe, is associated with periodontitis,
a disease that in some form affects up to 80% of the adult population in the USA. The …

Hydrolysis of Epithelial Junctional Proteins by Porphyromonas gingivalis Gingipains

J Katz, QB Yang, P Zhang, J Potempa… - Infection and …, 2002 - Am Soc Microbiol
Porphyromonas gingivalis has been implicated as an etiologic agent of adult periodontitis.
We have previously shown that P. gingivalis can degrade the epithelial cell-cell junction …

Maturation of fimbria precursor protein by exogenous gingipains in Porphyromonas gingivalis gingipain-null mutant

T Kato, T Tsuda, H Omori, T Kato… - FEMS microbiology …, 2007 - academic.oup.com
Porphyromonas gingivalis expresses several virulence factors such as fimbriae and
proteases, termed gingipains, which are enzymes that process precursor fimbriae proteins …

Role of fimbriae in Porphyromonas gingivalis invasion of gingival epithelial cells

A Weinberg, CM Belton, Y Park… - Infection and …, 1997 - Am Soc Microbiol
Porphyromonas gingivalis is a periodontal pathogen capable of invading primary cultures of
normal human gingival epithelial cells (NHGEC). Involvement of P. gingivalis fimbriae in the …

Porphyromonas gingivalis gingipains mediate the shedding of syndecan‐1 from the surface of gingival epithelial cells

E Andrian, D Grenier… - Oral microbiology and …, 2006 - Wiley Online Library
Porphyromonas gingivalis gingipains are thought to be critical virulence factors in
periodontitis. Increased serum levels of the soluble ectodomains of surface effectors have …

Glyceraldehyde-3-Phosphate Dehydrogenase of Streptococcus oralis Functions as a Coadhesin for Porphyromonas gingivalis Major Fimbriae

K Maeda, H Nagata, Y Yamamoto, M Tanaka… - Infection and …, 2004 - Am Soc Microbiol
Cohesive interactions between Porphyromonas gingivalis and plaque-forming bacteria,
such as Streptococcus oralis, are considered to play an important role in the colonization of …

Invasion of Epithelial Cells and Proteolysis of Cellular Focal Adhesion Components by Distinct Types of Porphyromonas gingivalis Fimbriae

I Nakagawa, H Inaba, T Yamamura, T Kato… - Infection and …, 2006 - Am Soc Microbiol
Porphyromonas gingivalis fimbriae are classified into six types (types I to V and Ib) based on
the fimA genes encoding FimA (a subunit of fimbriae), and they play a critical role in …

Effect of Inactivation of the Arg- and/or Lys-Gingipain Gene on Selected Virulence and Physiological Properties of Porphyromonas gingivalis

D Grenier, S Roy, F Chandad, P Plamondon… - Infection and …, 2003 - Am Soc Microbiol
Proteolytic enzymes produced by Porphyromonas gingivalis are thought to play critical roles
in the pathogenesis of periodontitis. The aim of this study was to investigate the effect of …