Tumor angiogenesis revisited: regulators and clinical implications
Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
[HTML][HTML] Tumor angiogenesis: Current challenges and therapeutic opportunities
FH Al-Ostoot, S Salah, HA Khamees… - Cancer treatment and …, 2021 - Elsevier
Angiogenesis plays an important role in the development of cancer since it allows for the
delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant …
delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant …
[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …
is a main driving force in many severe human diseases including cancer. As such, tumor …
Tumor neovascularization and developments in therapeutics
Y Katayama, J Uchino, Y Chihara, N Tamiya, Y Kaneko… - Cancers, 2019 - mdpi.com
Tumors undergo fast neovascularization to support the rapid proliferation of cancer cells.
Vasculature in tumors, unlike that in wound healing, is immature and affects the tumor …
Vasculature in tumors, unlike that in wound healing, is immature and affects the tumor …
[PDF][PDF] Mechanisms and future directions for angiogenesis-based cancer therapies
FA Scappaticci - Journal of clinical oncology, 2002 - Citeseer
Targeting angiogenesis represents a new strategy for the development of anticancer
therapies. New targets derived from proliferating endothelial cells may be useful in …
therapies. New targets derived from proliferating endothelial cells may be useful in …
Angiogenesis and cancer: a cross-talk between basic science and clinical trials (the “do ut des” paradigm)
G de Castro Junior, F Puglisi, E de Azambuja… - Critical reviews in …, 2006 - Elsevier
Angiogenesis plays a crucial role in facilitating tumor growth and the metastatic process, and
it is the result of a dynamic balance between pro-angiogenic factors, like vascular …
it is the result of a dynamic balance between pro-angiogenic factors, like vascular …
Overview of angiogenesis: biologic implications for antiangiogenic therapy
Tumor angiogenesis is essential for the growth of primary and metastatic tumors. This
process requires the coordinated activities of multiple factors and cell types. For tumors to …
process requires the coordinated activities of multiple factors and cell types. For tumors to …
Targeting vascular endothelial growth factor and angiogenesis for the treatment of colorectal cancer
TS Collins, HI Hurwitz - Seminars in oncology, 2005 - Elsevier
Angiogenesis, the development and proliferation of new blood vessels, is critical for the
growth of tumors. The process of new blood vessel formation is under complex control from …
growth of tumors. The process of new blood vessel formation is under complex control from …
Tumor angiogenesis: insights and innovations
F Nussenbaum, IM Herman - Journal of oncology, 2010 - Wiley Online Library
Angiogenesis is a vital process resulting in the formation of new blood vessels. It is normally
a highly regulated process that occurs during human development, reproduction, and …
a highly regulated process that occurs during human development, reproduction, and …
Angiogenesis in cancer: molecular mechanisms, clinical impact
ME Eichhorn, A Kleespies, MK Angele… - … Archives of Surgery, 2007 - Springer
Background Angiogenesis, the formation of new blood vessels from the endothelium of the
existing vasculature, is fundamental in tumor growth, progression, and metastasis. Inhibiting …
existing vasculature, is fundamental in tumor growth, progression, and metastasis. Inhibiting …