Fibrinogen influx and accumulation of cross-linked fibrin in mouse carcinomas

LF Brown, B Asc, VS Harvey, B Buchinski, HF Dvorak - Cancer research, 1988 - AACR
Abstract 125I-radiolabeled guinea pig fibrinogen was used to measure the influx (20 min)
and accumulation (18 h) of fibrinogen/fibrin in three transplantable carcinomas (Lewis lung …

Quantitation of fibrinogen influx and fibrin deposition and turnover in line 1 and line 10 guinea pig carcinomas

HF Dvorak, VS Harvey, J McDonagh - Cancer research, 1984 - AACR
Radiolabeled guinea pig fibrinogen (GPF) was used to measure fibrinogen influx and fibrin
accumulation in line 1 and line 10 hepato-(bile duct) carcinomas growing in the sc space of …

Fibrinogen metabolism in experimental tumours

HI Peterson, KL Appelgren, BHO Rosengren - European Journal of Cancer …, 1969 - Elsevier
The uptake of intravenously injected labelled mouse and rat fibrinogen in two transplantable
mouse tumours was studied. A high uptake occurred in tumours compared to normal tissues …

Experimental studies on the mechanisms of fibrinogen uptake in a rat tumour

HI Peterson, KL Appelgren, BHO Rosengren - European Journal of Cancer …, 1972 - Elsevier
The uptake of intravenously administered labelled rat fibrinogen in a transplanted rat tumour
and in different normal tissues of the rat was studied and related to the thromboplastic …

Fibrinogen influx and accumulation of cross-linked fibrin in healing wounds and in tumor stroma.

LF Brown, L Van de Water, VS Harvey… - The American journal of …, 1988 - ncbi.nlm.nih.gov
Fibrinogen enters wounds and solid tumors, where it is clotted to fibrin that may
subsequently be replaced by collagenous stroma. If, as has been suggested, the …

Fibrinogen and tumor cell metastasis.

JS Palumbo, JL Degen - Haemostasis, 2001 - europepmc.org
Detailed studies tumor cell-associated procoagulants and fibrinolytic factors have strongly
suggested that local thrombin and plasmin generation may be important in tumor …

Localization of radioiodinated rat fibrinogen in transplanted rat tumors

ED Day, JA Planinsek… - Journal of the National …, 1959 - academic.oup.com
Radioiodinated rat fibrinogen localized in three different transplantable rat tumors during the
initial inflammatory reaction of the host to the implant and during the rapid growth stage of …

Demonstration of fibrin in early stages of experimental metastases

EC Chew, AC Wallace - Cancer Research, 1976 - AACR
Tumor emboli were produced in lungs of Sprague-Dawley rats by iv injection of Walker 256
tumor cells into the tail vein. Tissues were examined by electron microscopy at periods from …

Uptake of fibrinogen and fibrinolytic enzymes by neoplastic tissue

N Back, RR Shields, G DeWitt… - Journal of the …, 1966 - academic.oup.com
With the aid of radioisotopic and indirect immunofluorescence techniques, human fibrinogen
and urokinase-activated human plasmin were found to localize in transplanted Murphy …

Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice

JS Palumbo, JM Potter, LS Kaplan, K Talmage… - Cancer research, 2002 - AACR
Previous studies of tumor cell-associated procoagulants and fibrinolytic factors have strongly
suggested that local thrombin and plasmin generation may be important in tumor growth and …