Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic‑active infection, periodontitis and systemic inflammation

S Kim, Y Bando, C Chang, J Kwon… - International …, 2022 - spandidos-publications.com
Porphyromonas gingivalis (Pg), one of the 'red‑complex'perio‑pathogens known to play a
critical role in the development of periodontitis, has been used in various animal models to …

Oral infection with Porphyromonas gingivalis and systemic cytokine profile in C57BL/6.KOR‐ApoEshl mice

S Miyauchi, T Maekawa, Y Aoki… - Journal of …, 2012 - Wiley Online Library
Miyauchi S, Maekawa T, Aoki Y, Miyazawa H, Tabeta K, Nakajima T, Yamazaki K. Oral
infection with Porphyromonas gingivalis and systemic cytokine profile in C57BL/6. KOR …

Animal models for Porphyromonas gingivalis-mediated periodontal disease

CA Genco, T Van Dyke, S Amar - Trends in microbiology, 1998 - cell.com
Porphyromonas gingivalis is one of the principal pathogens in the development of adult
periodontitis. Several different animal models have been used to evaluate the complex …

Periodontitis induced by Porphyromonas gingivalis drives impaired glucose metabolism in mice

N Kang, Y Zhang, F Xue, J Duan, F Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
Periodontitis has been demonstrated to be bidirectionally associated with diabetes and has
been recognized as a complication of diabetes. As a periodontal pathogen, Porphyromonas …

Effect of host responses on the pathogenicity of strains of Porphyromonas gingivalis

J Katz, DC Ward, SM Michalek - Oral microbiology and …, 1996 - Wiley Online Library
Porphyromonas gingivalis is implicated in the etiology of periodontitis. Strains of P.
gingivalis have been classified as invasive or noninvasive based on their ability to form …

Porphyromonas Gingivalis and Dextran Sulfate Sodium Induce Periodontitis Through the Disruption of Physical Barriers in Mice

YS Choi, YC Kim, AR Jo, S Ji, KT Koo… - European journal of …, 2013 - journals.sagepub.com
Periodontitis is a chronic inflammatory disease caused by the interaction of plaque-
associated bacteria with host cells. Gingival epithelial barriers provide the first line of …

Inflammatory response of gut, spleen, and liver in mice induced by orally administered Porphyromonas gingivalis

Y Liu, W Huang, K Dai, N Liu, J Wang, X Lu… - Journal of Oral …, 2022 - Taylor & Francis
Background Periodontitis is a chronic multifactorial inflammatory disease. Porphyromonas
gingivalis is a primary periopathogen in the initiation and development of periodontal …

[HTML][HTML] Mouse periodontitis models using whole Porphyromonas gingivalis bacteria induction

N Hariyani, AN Halimah, M Al-Junaid, O Fadhila… - The Saudi Dental …, 2021 - Elsevier
Introduction Due to the increasing prevalence of periodontitis within the general population,
it is important to study the progress and stages of periodontal disease and the efficacy of …

Dual lifestyle of Porphyromonas gingivalis in biofilm and gingival cells

A Sakanaka, H Takeuchi, M Kuboniwa, A Amano - Microbial pathogenesis, 2016 - Elsevier
Porphyromonas gingivalis is deeply involved in the pathogenesis of marginal periodontitis,
and recent findings have consolidated its role as an important and unique pathogen. This …

Porphyromonas gingivalis-induced inflammatory mediator profile in an ex vivo human whole blood model

C Bodet, F Chandad, D Grenier - Clinical & Experimental …, 2006 - academic.oup.com
Periodontitis is characterized by an accumulation of inflammatory cells in periodontal tissue
and subgingival sites. Leukocytes play a major role in the host response to Porphyromonas …