The κ opioid receptor and food intake
Many studies have suggested a role of opioid receptors in the modulation of food intake.
Several distinct classes of opioid receptors have been postulated. In an attempt to establish …
Several distinct classes of opioid receptors have been postulated. In an attempt to establish …
Reward systems and food intake: role of opioids
BA Gosnell, AS Levine - International journal of obesity, 2009 - nature.com
Humans eat for many reasons, including the rewarding qualities of foods. A host of
neurotransmitters have been shown to influence eating behavior and some of these appear …
neurotransmitters have been shown to influence eating behavior and some of these appear …
Mu‐opioid receptor knockout mice show diminished food‐anticipatory activity
MJH Kas, R Van Den Bos, AM Baars… - European Journal of …, 2004 - Wiley Online Library
We have previously suggested that during or prior to activation of anticipatory behaviour to a
coming reward, µ‐opioid receptors are activated. To test this hypothesis schedule induced …
coming reward, µ‐opioid receptors are activated. To test this hypothesis schedule induced …
Reversible suppression of food reward behavior by chronic mu-opioid receptor antagonism in the nucleus accumbens
AC Shin, PJ Pistell, CB Phifer, HR Berthoud - Neuroscience, 2010 - Elsevier
Overindulgence in easily available energy-dense palatable foods is thought to be an
important factor in the current obesity epidemic but the underlying neural mechanisms are …
important factor in the current obesity epidemic but the underlying neural mechanisms are …
Diet-induced obesity increases μ opioid receptor binding in specific regions of the rat brain
SL Smith, JA Harrold, G Williams - Brain research, 2002 - Elsevier
Mu (μ) opioid agonists preferentially increase the intake of highly palatable food. Here we
investigated changes in μ opioid binding in feeding-and reward-related brain regions in rats …
investigated changes in μ opioid binding in feeding-and reward-related brain regions in rats …
Endogenous opioid modulation of food intake and body weight: Implications for opioid influences upon motivation and addiction
RJ Bodnar - Peptides, 2019 - Elsevier
This review is part of a special issue dedicated to Opioid addiction, and examines the
influential role of opioid peptides, opioid receptors and opiate drugs in mediating food intake …
influential role of opioid peptides, opioid receptors and opiate drugs in mediating food intake …
Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food
Binge eating and an increased role for palatability in determining food intake are abnormal
adaptations in feeding behavior linked to eating disorders and body weight dysregulation …
adaptations in feeding behavior linked to eating disorders and body weight dysregulation …
Induction of hyperphagia and carbohydrate intake by μ-opioid receptor stimulation in circumscribed regions of frontal cortex
JD Mena, K Sadeghian, BA Baldo - Journal of Neuroscience, 2011 - Soc Neuroscience
Frontal cortical regions are activated by food-associated stimuli, and this activation appears
to be dysregulated in individuals with eating disorders. Nevertheless, frontal control of basic …
to be dysregulated in individuals with eating disorders. Nevertheless, frontal control of basic …
Decreased consumption of sweet fluids in mu opioid receptor knockout mice: a microstructural analysis of licking behavior
SB Ostlund, A Kosheleff, NT Maidment… - Psychopharmacology, 2013 - Springer
Rationale Evidence suggests that the palatability of food (ie, the hedonic impact produced
by its sensory features) can promote feeding and may underlie compulsive eating, leading to …
by its sensory features) can promote feeding and may underlie compulsive eating, leading to …
Opioids as facilitators of feeding: can any food be rewarding?
Palatability is one of the most rewarding aspects of consummatory behavior. Opioids, potent
facilitators of intake of sweet and fat tastants, are thought to mediate hedonics of feeding …
facilitators of intake of sweet and fat tastants, are thought to mediate hedonics of feeding …