Immunology of membranous nephropathy: from animal models to humans

RA Sinico, N Mezzina, B Trezzi… - Clinical & …, 2016 - academic.oup.com
Membranous nephropathy (MN), the leading cause of nephrotic syndrome in adults, is
characterized by the deposition of subepithelial immune deposits that consist mainly of …

Idiopathic membranous nephropathy: an autoimmune disease

SP Makker, A Tramontano - Seminars in nephrology, 2011 - Elsevier
For more than 50 years researchers have debated the evidence for an autoimmune basis of
human idiopathic membranous nephritis (MN). Work published in the past 2 years has …

The pathogenesis of idiopathic membranous nephropathy: a 50-year odyssey

RJ Glassock - American Journal of Kidney Diseases, 2010 - Elsevier
Ever since its first delineation as a distinct clinicopathologic entity in 1957, idiopathic
membranous nephropathy (MN) has been the subject of intense laboratory and clinical …

Pathogenesis of membranous nephropathy: a new paradigm in evolution

RJ Glassock - New Insights into Glomerulonephritis, 2013 - karger.com
Membranous nephropathy (MN) has been recognized as a distinct morphological entity for
over 50 years, but it is only recently that the underlying pathogenesis of the primary form of …

The role of complement in membranous nephropathy

H Ma, DG Sandor, LH Beck Jr - Seminars in nephrology, 2013 - Elsevier
Membranous nephropathy (MN) describes a histopathologic pattern of injury marked by
glomerular subepithelial immune deposits and collectively represents one of the most …

Membranous glomerulonephritis: histological and serological features to differentiate cancer-related and non-related forms

C Murtas, GM Ghiggeri - Journal of Nephrology, 2016 - Springer
Membranous nephropathy is a frequent cause of nephrotic syndrome in adults. In most
patients, it appears as a primary renal disease but in about 20% of cases membranous …

[HTML][HTML] Membranous nephropathy: recent travels and new roads ahead

LH Beck Jr, DJ Salant - Kidney international, 2010 - Elsevier
Insights from experimental studies have been recently translated into substantial advances
in understanding the pathogenesis of human membranous nephropathy (MN). These …

Revisiting immunological and clinical aspects of membranous nephropathy

I Nieto-Gañán, I Iturrieta-Zuazo, C Rita… - Clinical …, 2022 - Elsevier
Idiopathic or primary membranous nephropathy (IMN) is one of the most frequent causes of
nephrotic syndrome in adults and the elderly. It is characterized by a thickening of the wall of …

New insights into the pathogenesis of membranous glomerulonephritis

P Ronco, H Debiec - Current Opinion in Nephrology and …, 2006 - journals.lww.com
Membranous nephropathy most likely is a heterogeneous disease, although a common
denominator may be that podocytes provide antigenic targets for in-situ formation of …

Is primary membranous nephropathy a complement mediated disease?

L Reinhard, RAK Stahl, E Hoxha - Molecular Immunology, 2020 - Elsevier
Membranous nephropathy (MN) is an immune complex mediated disease. Although limited
to the kidney, in up to 20% of patients MN is associated with other autoimmune, infectious or …