Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs
Abstract Alzheimer's disease (AD), also called senile dementia, is the most common
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …
Update on the pharmacological treatment of Alzheimer's disease
F Massoud, S Gauthier - Current neuropharmacology, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder. Worldwide
prevalence of the disease is estimated at more than 24 million cases. With aging of …
prevalence of the disease is estimated at more than 24 million cases. With aging of …
Pharmacotherapy of Alzheimer's disease: Seeking clarity in a time of uncertainty
Alzheimer's disease (AD) is recognized as a major health hazard that mostly affects people
older than 60 years. AD is one of the biggest medical, economic, and social concerns to …
older than 60 years. AD is one of the biggest medical, economic, and social concerns to …
Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development
BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
Developing effective Alzheimer's disease therapies: clinical experience and future directions
DR Elmaleh, MR Farlow, PS Conti… - Journal of …, 2019 - content.iospress.com
Alzheimer's disease (AD) clinical trials, focused on disease modifying drugs and conducted
in patients with mild to moderate AD, as well as prodromal (early) AD, have failed to reach …
in patients with mild to moderate AD, as well as prodromal (early) AD, have failed to reach …
Role of aducanumab in the treatment of Alzheimer's disease: Challenges and opportunities
M Vaz, V Silva, C Monteiro… - Clinical interventions in …, 2022 - Taylor & Francis
Aducanumab is a monoclonal antibody selective for amyloid β (Aβ) aggregates. In June
2021, aducanumab became the first drug underlying the pathophysiology of Alzheimer's …
2021, aducanumab became the first drug underlying the pathophysiology of Alzheimer's …
New and emerging treatments for Alzheimer's disease
Alzheimer's disease (AD) and other dementias represent a significant and increasing clinical
challenge. This review highlights current treatment options for AD and the main focusses of …
challenge. This review highlights current treatment options for AD and the main focusses of …
Alzheimer's disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?
K Mullane, M Williams - Biochemical pharmacology, 2020 - Elsevier
Alzheimer's Disease (AD) therapeutics based on the amyloid hypothesis have repeatedly
failed in clinical trials. Together with numerous reports that amyloid is present in brains from …
failed in clinical trials. Together with numerous reports that amyloid is present in brains from …
Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions
A Abeysinghe, R Deshapriya, C Udawatte - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder and is identified as the most
common cause for dementia. Despite huge global economic burden and the impact on the …
common cause for dementia. Despite huge global economic burden and the impact on the …
Recent developments in Alzheimer's disease therapeutics
MS Rafii, PS Aisen - BMC medicine, 2009 - Springer
Alzheimer's disease is a devastating neurological disorder that affects more than 37 million
people worldwide. The economic burden of Alzheimer's disease is massive; in the United …
people worldwide. The economic burden of Alzheimer's disease is massive; in the United …