[HTML][HTML] Clinical trials of new drugs for Alzheimer disease: a 2020–2023 update
LK Huang, YC Kuan, HW Lin, CJ Hu - Journal of Biomedical Science, 2023 - Springer
Alzheimer's disease (AD) is the leading cause of dementia, presenting a significant unmet
medical need worldwide. The pathogenesis of AD involves various pathophysiological …
medical need worldwide. The pathogenesis of AD involves various pathophysiological …
Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors
Alzheimer's disease (AD) is the most common cause of memory impairment and dementia in
the elderly. AD is pathologically characterized by extracellular deposits of beta-amyloid (Aβ) …
the elderly. AD is pathologically characterized by extracellular deposits of beta-amyloid (Aβ) …
[HTML][HTML] Current understanding of the physiopathology, diagnosis and therapeutic approach to Alzheimer's disease
V García-Morales, A González-Acedo… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia. It is characterized by
cognitive decline and progressive memory loss. The aim of this review was to update the …
cognitive decline and progressive memory loss. The aim of this review was to update the …
[HTML][HTML] “Aducanumab” making a comeback in Alzheimer's disease: An old wine in a new bottle
Despite presence of substantial evidence suggesting the pivotal role of amyloid (Aβ) in
Alzheimer's disease (AD), very few therapeutic agents have been able to ameliorate the …
Alzheimer's disease (AD), very few therapeutic agents have been able to ameliorate the …
Have there been improvements in Alzheimer's disease drug discovery over the past 5 years?
R Cacabelos - Expert opinion on drug discovery, 2018 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is the most important neurodegenerative disorder
with a global cost worldwide of over $700 billion. Pharmacological treatment accounts for 10 …
with a global cost worldwide of over $700 billion. Pharmacological treatment accounts for 10 …
Therapies for prevention and treatment of Alzheimer's disease
J Mendiola-Precoma, LC Berumen… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …
[HTML][HTML] Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease
K Kumar, A Kumar, RM Keegan… - Biomedicine & …, 2018 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by
progressive deterioration of cognitive functions. The pathological hallmarks are extracellular …
progressive deterioration of cognitive functions. The pathological hallmarks are extracellular …
[HTML][HTML] Natural products-based drugs: potential therapeutics against Alzheimer's disease and other neurological disorders
Alzheimer's disease (AD) and dementia are disorders of the aging population and becoming
major health care burden worldwide due to unavailability of complete therapy. AD is the …
major health care burden worldwide due to unavailability of complete therapy. AD is the …
[HTML][HTML] Small-molecule theranostics in Alzheimer's disease
Á Sarabia-Vallejo, P López-Alvarado… - European Journal of …, 2023 - Elsevier
Alzheimer's Disease (AD) remains one of the most challenging health-related issues for our
society. It is becoming increasingly prevalent, especially in developed countries, due to the …
society. It is becoming increasingly prevalent, especially in developed countries, due to the …