Genetic, epigenetic and transcription factors in atrial fibrillation

OV Sapelnikov, AA Kulikov, OO Favorova… - Rational …, 2019 - rpcardio.elpub.ru
Atrial fibrillation (AF) is one of the most common arrhythmia that occurs in patients with
cardiovascular diseases. Congenital forms of AF are quite rare. Many studies have shown …

Genetics of atrial fibrillation: rare mutations, common variants and clinical relevance?

MF Sinner, A Pfeufer, S Kääb - Herzschrittmachertherapie & …, 2006 - Springer
Atrial fibrillation (AF) is considered the, by far, the most common arrhythmia of man, affecting
millions of patients worldwide. The high socio-economic relevance is due to several severe …

New insights into the molecular basis of atrial fibrillation: mechanistic and therapeutic implications

D Dobrev, S Nattel - Cardiovascular research, 2011 - academic.oup.com
Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with substantial
cardiovascular morbidity and mortality, with stroke being the most critical complication. 1 …

[HTML][HTML] Recent advances in the molecular pathophysiology of atrial fibrillation

R Wakili, N Voigt, S Kääb, D Dobrev… - The Journal of clinical …, 2011 - Am Soc Clin Investig
Atrial fibrillation (AF) is an extremely common cardiac rhythm disorder that causes
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …

The European network for translational research in atrial fibrillation (EUTRAF): objectives and initial results

U Schotten, S Hatem, U Ravens, P Jaïs, FU Müller… - EP …, 2015 - academic.oup.com
Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As
an age-related arrhythmia AF is becoming a huge socio-economic burden for European …

[HTML][HTML] Genetics of Atrial Fibrillation

R Brugada, S Kaab - Manual of Surgical Treatment of Atrial Fibrillation, 2008 - escardio.org
Molecular biology and genetics are giving and will continue to give new insights into the
development of cardiac diseases. Arrhythmias like AF will undoubtedly benefit from the …

Molecular basis of atrial fibrillation: a dream or a reality?

DR Van Wagoner - Journal of cardiovascular electrophysiology, 2003 - europepmc.org
AF is a difficult disease to treat because of the numerous (ischemic, metabolic, inflammatory,
structural) mechanisms contributing to its etiology. AF persistence requires both an …

Biology of the substrate of atrial fibrillation

S Hatem - Biologie aujourd'hui, 2012 - europepmc.org
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia in clinical practice, is
often associated with progressive dilatation and remodeling of the atria which constitute the …

Genetics of atrial fibrillation: state of the art in 2017

D Fatkin, CF Santiago, IG Huttner, SA Lubitz… - Heart, Lung and …, 2017 - Elsevier
Genetic variation is an important determinant of atrial fibrillation (AF) susceptibility.
Numerous rare variants in protein-coding sequences of genes have been associated with …

Genetics of Atrial Fibrillation: The Clinician's Perspective

R Brugada, S Kääb - Atrial fibrillation: from bench to bedside, 2008 - Springer
Atrial fibrillation (AF) remains one of the most challenging arrhythmias for the clinician and
basic researcher. Different approaches have been undertaken from the basic standpoint to …