Albeit essential for perpetuation of species, reproduction is an energy-demanding function
that can be adjusted to body metabolic status. Reproductive maturation and function can be …

The neurohormonal control of reproduction involves a hierarchical network of central and
peripheral signals in the hypothalamic–pituitary–gonadal (HPG) axis. Development and …

BACKGROUND Puberty is a complex developmental event, controlled by sophisticated
regulatory networks that integrate peripheral and internal cues and impinge at the brain …

It is well established that pubertal activation of the reproductive axis and maintenance of
fertility are critically dependent on the magnitude of body energy reserves and the metabolic …

Reproductive function is tightly regulated by an intricate network of central and peripheral
factors; however, the precise mechanism triggering critical reproductive events, such as …

Highly sophisticated and synchronized interactions of various cells and hormonal signals
are required to make organisms competent for reproduction. GnRH neurons act as a …

Mammalian reproductive function includes puberty onset and completion, reproductive
cyclicity, steroidogenesis, gametogenesis, fertilization, pregnancy, and lactation; all are …

BACKGROUND The discovery of kisspeptin as key central regulator of GnRH secretion has
led to a new level of understanding of the neuroendocrine regulation of human reproduction …

Mammalian reproductive function is a complex system of many players orchestrated by the
hypothalamus-pituitary–gonadal (HPG) axis. The hypothalamic gonadotropin-releasing …

Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the
physiological menstrual cycle including the release of gonadotrophins to stimulate follicular …