Determination of danshensu in rat plasma and tissues by high-performance liquid chromatography

Z Zhang, M Xu, S Sun, H Guo, X Qiao… - Journal of …, 2008 - academic.oup.com
A systematic study on pharmacokinetcs and tissue distribution of danshensu (one of the
major active components from Salvia miltiorrhiza) is conducted using a rapid and sensitive …

Determination of danshensu in urine and its pharmacokinetics in human

Q Liu, RB Chao - Yao xue xue bao= Acta Pharmaceutica Sinica, 2003 - europepmc.org
To determine Danshensu in urine and study its pharmacokinetics in human. A solid phase
extraction-HPLC method was used for determination of Danshensu in urine of human. HPLC …

Determination and pharmacokinetics of danshensu in rat plasma after oral administration of danshen extract using liquid chromatography/tandem mass spectrometry

W Li, ZW Li, JP Han, XX Li, J Gao, CX Liu - European journal of drug …, 2008 - Springer
A liquid chromatography/tandem mass spectrometry (LC/MS/MS) method was developed
and validated for the determination and pharmacokinetics of danshensu in rat plasma …

Simultaneous determination and pharmacokinetic study of water‐soluble and lipid‐soluble components of danshen in rat plasma using HPLC‐UV method

X Wang, ZR Zhang, H Fu, J Liu, Q Chen… - Biomedical …, 2007 - Wiley Online Library
A sensitive and specific HPLC‐UV method was developed for the simultaneous
determination of major active components of danshen in rat plasma. Both water‐soluble and …

Identification of a major metabolite of danshensu in rat urine and simultaneous determination of danshensu and its metabolite in plasma: Application to a …

X Wang, W Li, X Ma, K Yan, Y Chu… - Drug Testing and …, 2015 - Wiley Online Library
Danshensu, as the effective component of Salvia miltiorrhiza (Danshen), has been widely
used in clinical studies for treatment of cardiovascular diseases in China. A new metabolite …

New metabolite profiles of Danshensu in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry

J Gu, L Feng, M Zhang, D Qin, J Jiang, X Cheng… - … of Chromatography B, 2014 - Elsevier
In our research, ultraperformance liquid chromatography/quadrupole-time-of-flight mass
spectrometry (U-HPLC/Q-TOF-MS) was established for analyzing the metabolite profiles of …

Determination of Danshensu, a major active compound of Radix Salvia miltiorrhiza in dog plasma by HPLC with fluorescence detection

X Luo, K Bi, S Zhou, Q Wei… - Biomedical …, 2001 - Wiley Online Library
A simple and sensitive high performance liquid chromatography method has been
developed for the determination of Danshensu (3, 4‐dihydroxyphenyllactic acid) in dog …

Improved quality evaluation of Radix Salvia miltiorrhiza through simultaneous quantification of seven major active components by high‐performance liquid …

HL Ma, MJ Qin, LW Qi, G Wu… - Biomedical …, 2007 - Wiley Online Library
A novel method, using high‐performance liquid chromatography combined with principal
component analysis, was developed for the quality evaluation of danshen through …

Comparative pharmacokinetic study of sodium Danshensu and Salvia miltiorrhiza injection in rat

J Wang, Z Ma, W Wang, Z Hong… - Zhongguo Zhong yao za …, 2009 - europepmc.org
Objective To develop a HPLC method for determination of the concentration of Danshensu
in rat plasma and undertake comparative pharmacokinetic study of sodium danshensu and …

Effects of salvianolic acid B on the pharmacokinetics of danshensu in Danshen injection in rats.

YD Yu Dan, CJG Chai JianGuo, CYG Cao YanGuang… - 2009 - cabidigitallibrary.org
Aim: To study the pharmacokinetic effects of salvianolic acid B (Sal B) on danshensu (DSS)
in Danshen injection in rats. Method: Following the intravenous administration of Danshen …