[HTML][HTML] Time-series reconstruction of the molecular architecture of human centriole assembly

MH Laporte, D Gambarotto, É Bertiaux, L Bournonville… - Cell, 2024 - cell.com
Centriole biogenesis, as in most organelle assemblies, involves the sequential recruitment
of sub-structural elements that will support its function. To uncover this process, we …

Centriole biogenesis: from identifying the characters to understanding the plot

N Banterle, P Gönczy - Annual review of cell and developmental …, 2017 - annualreviews.org
The centriole is a beautiful microtubule-based organelle that is critical for the proper
execution of many fundamental cellular processes, including polarity, motility, and division …

Superresolution characterization of core centriole architecture

Y Tian, C Wei, J He, Y Yan, N Pang, X Fang… - Journal of Cell …, 2021 - rupress.org
The centrosome is the main microtubule-organizing center in animal cells. It comprises of
two centrioles and the surrounding pericentriolar material. Protein organization at the outer …

Deconstructing the centriole: structure and number control

DA Brito, SM Gouveia, M Bettencourt-Dias - Current opinion in cell biology, 2012 - Elsevier
Centrioles are very small microtubule-based organelles essential for centrosome, cilia and
flagella assembly, which are involved in a variety of cellular and developmental processes …

[HTML][HTML] With age comes maturity: biochemical and structural transformation of a human centriole in the making

C Sullenberger, A Vasquez-Limeta, D Kong… - Cells, 2020 - mdpi.com
Centrioles are microtubule-based cellular structures present in most human cells that build
centrosomes and cilia. Proliferating cells have only two centrosomes and this number is …

[HTML][HTML] Molecular architecture of a cylindrical self-assembly at human centrosomes

TS Kim, L Zhang, J Il Ahn, L Meng, Y Chen… - Nature …, 2019 - nature.com
The cell is constructed by higher-order structures and organelles through complex
interactions among distinct structural constituents. The centrosome is a membraneless …

Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control

LC Keller, S Geimer, E Romijn, J Yates III… - Molecular biology of …, 2009 - Am Soc Cell Biol
Centrioles are intriguing cylindrical organelles composed of triplet microtubules. Proteomic
data suggest that a large number of proteins besides tubulin are necessary for the formation …

Building a ninefold symmetrical barrel: structural dissections of centriole assembly

G Dong - Open biology, 2015 - royalsocietypublishing.org
Centrioles are short microtubule-based organelles with a conserved ninefold symmetry.
They are essential for both centrosome formation and cilium biogenesis in most eukaryotes …

[HTML][HTML] High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy

M Bowler, D Kong, S Sun, R Nanjundappa… - Nature …, 2019 - nature.com
Centrioles are vital cellular structures that form centrosomes and cilia. The formation and
function of cilia depends on a set of centriole's distal appendages. In this study, we use …

Once and only once: mechanisms of centriole duplication and their deregulation in disease

EA Nigg, AJ Holland - Nature reviews Molecular cell biology, 2018 - nature.com
Centrioles are conserved microtubule-based organelles that form the core of the centrosome
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …