Ex-vivo study of flow dynamics and endothelial cell structure during extended hypothermic machine perfusion preservation of livers

S Jain, H Xu, H Duncan, JW Jones Jr, JX Zhang… - Cryobiology, 2004 - Elsevier
Liver transplantation is often the only effective treatment for end stage liver diseases
resulting from cirrhosis, hepatitis, progressive jaundice, and biliary atresia. Hypothermic …

Pronlonged hypothermic machine perfusion preserves hepatocellular function but potentiates endothelial cell dysfunction in rat livers

H Xu, CY Lee, MG Clemens, JX Zhang - Transplantation, 2004 - journals.lww.com
Background. Although hypothermic machine perfusion (HMP) preservation has been shown
to improve organ function and to expand the organ donor pool, problems still exist with the …

HETEROGENEOUS FLOW PATTERNS DURING HYPOTHERMIC MACHINE PERFUSION PRESERVATION OF LIVERS1

CY Lee, JX Zhang, H DeSilva, RN Coger… - …, 2000 - journals.lww.com
Background. Hypothermic machine perfusion preservation (MPP) has the potential to relieve
the current donor shortage problem by providing superior preserved tissue and viable non …

Hypothermic machine preservation attenuates ischemia/reperfusion markers after liver transplantation: preliminary results

JV Guarrera, SD Henry, SWC Chen, T Brown… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Hypothermic machine perfusion (HMP) has shown significant benefits in
renal transplantation but is still in its infancy in liver transplantation. Potential benefits …

Does hypothermic machine perfusion of human donor livers affect risks of sinusoidal endothelial injury and microbial infection? A feasibility study assessing flow …

A Jomaa, K Gurusamy, PN Siriwardana… - Transplantation …, 2013 - Elsevier
BACKGROUND: Hypothermic machine perfusion (HMP) is better than conventional cold
storage in kidney transplantation. Large animal models suggest that HMP may be beneficial …

Functional recovery of preserved livers following warm ischemia: improvement by machine perfusion preservation

CY Lee, JX Zhang, JW Jones Jr, JH Southard… - …, 2002 - journals.lww.com
Background. Hypothermic machine perfusion preservation has the potential to relieve the
current donor shortage problem by reclaiming and preserving marginal donor organs …

[HTML][HTML] Oxygenated hypothermic machine perfusion after static cold storage improves endothelial function of extended criteria donor livers

LC Burlage, N Karimian, AC Westerkamp, N Visser… - Hpb, 2017 - Elsevier
Background Lack of oxygen and biomechanical stimulation during static cold storage (SCS)
of donor livers compromises endothelial cell function. We investigated the effect of end …

Flow competition between hepatic arterial and portal venous flow during hypothermic machine perfusion preservation of porcine livers

DR Monbaliu, C Debbaut… - … Journal of Artificial …, 2012 - journals.sagepub.com
Hypothermic machine perfusion (HMP) is regarded as a better preservation method for
donor livers than cold storage. During HMP, livers are perfused through the inlet blood …

Influence of flow and addition of oxygen during porcine liver hypothermic machine perfusion

K Vekemans, Q Liu, J Brassil, M Komuta… - Transplantation …, 2007 - Elsevier
INTRODUCTION: In contrast with kidneys, data on hypothermic machine perfusion (HMP) of
livers remain scarce. Optimal liver HMP is poorly defined. Superiority of liver HMP over …

[HTML][HTML] Hypothermic machine preservation reduces molecular markers of ischemia/reperfusion injury in human liver transplantation

SD Henry, E Nachber, J Tulipan, J Stone, C Bae… - American Journal of …, 2012 - Elsevier
Hypothermic machine perfusion (HMP) is in its infancy in clinical liver transplantation.
Potential benefits include diminished preservation injury (PI) and improved graft function …