Genome-wide association studies (GWASs) have identified single-nucleotide variations
(SNVs), which are common genetic variants that confer little individual risk but, considered …

Polygenic risk scores (PRSs) have been consistently associated with elevated breast cancer
risk in cohort studies and are associated with risk in both women with and those without a …

In this issue of the Journal, Shieh et al. report findings from an assessment of performance of
a polygenic risk score (PRS) for breast cancer in Latin American women (Latinas)(1). Study …

Importance Multiple polygenic risk scores (PRSs) for breast cancer have been developed
from large research consortia; however, their generalizability to diverse clinical settings is …

Abstract Background Polygenic risk scores (PRSs) have been demonstrated to identify
women of European, Asian, and Latino ancestry at elevated risk of developing breast cancer …

Purpose Polygenic risk scores (PRS) for breast cancer may help guide screening decisions.
However, few studies have examined whether PRS are associated with risk of short-term or …

PURPOSE Women with a family history of breast cancer are frequently referred for
hereditary cancer genetic testing, yet< 10% are found to have pathogenic variants in known …

Importance Polygenic risk scores (PRSs) have shown promise in breast cancer risk
prediction; however, limited studies have been conducted among Asian women. Objective …

Polygenic risk scores (PRSs) are increasingly being implemented to assess breast cancer
risk. This study aimed to assess and determine factors associated with uptake of PRS …

Population-based genomic screening is at the forefront of a new approach to disease
prevention. Yet the lack of diversity in genome wide association studies and ongoing …