Carnosine and crocin ameliorate oxidative stress in rats with rhabdomyolysis-induced acute kidney injury through upregulating HO-1 gene expression

NE El-Ashmawy, EG Khedr, AS Doghish, MS Elballal - Food Bioscience, 2022 - Elsevier
We aimed to investigate whether carnosine (a natural dipeptide found in humans) and
crocin (a natural product extracted from saffron and gardenia) can prevent the harmful …

Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin …

SN Chang, M Haroon, DK Dey, SC Kang - The Journal of Nutritional …, 2022 - Elsevier
Rhabdomyolysis induced acute kidney injury (RIAKI) is a life-threatening condition
responsible for approximately 19-58% of AKI cases worldwide. We performed an …

Protective effect of crocetin on hemorrhagic shock–induced acute renal failure in rats

Y Wang, J Yan, L Xi, Z Qian, Z Wang, L Yang - Shock, 2012 - journals.lww.com
Multiple organ failure is a common outcome of hemorrhagic shock followed by resuscitation,
and the kidney is one of the prime target organs involved. The main objective of the study …

Crocin reverses unilateral renal ischemia reperfusion injury-induced augmentation of oxidative stress and toll like receptor-4 activity

HO Abou-Hany, H Atef, E Said, HA Elkashef… - Environmental …, 2018 - Elsevier
Renal Ischemia (RI) usually develops as a secondary manifestation of hypertension, various
cardiovascular disorders and renal transplantation. It exerts hypoxic oxidative stress to …

Protective effect of thymol on glycerol-induced acute kidney injury

Q Wang, G Qi, H Zhou, F Cheng, X Yang, X Liu… - Renal failure, 2023 - Taylor & Francis
Acute kidney injury (AKI) is a syndrome characterized by an accelerating decrease in renal
function in a short time. Thymol is one of the main components of thyme species and has a …

[HTML][HTML] Penehyclidine hydrochloride pretreatment ameliorates rhabdomyolysis-induced AKI by activating the Nrf2/HO-1 pathway and allevi-ating endoplasmic …

W Zhao, XD Huang, LX Zhang, XJ Yang, LH Wang… - PLoS …, 2016 - journals.plos.org
Acute kidney injury (AKI) is one of the most severe complications of rhabdomyolysis (RM).
The underlying mechanisms and potential preventions need to be investigated …

[HTML][HTML] Protective effect of calcitriol on rhabdomyolysis-induced acute kidney injury in rats

NG Reis, HDC Francescato, LF de Almeida… - Scientific Reports, 2019 - nature.com
Glycerol injection in rats can lead to rhabdomyolysis, with the release of the intracellular
muscle content to the extracellular compartment and acute kidney injury (AKI). Oxidative …

Protective effect of naringin, a bioflavonoid on glycerol-induced acute renal failure in rat kidney

D Singh, V Chander, K Chopra - Toxicology, 2004 - Elsevier
Rhabdomyolysis-induced myoglobinuric acute renal failure accounts for about 10–40% of
all cases of acute renal failure (ARF). Reactive oxygen intermediates have been …

Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options

S Ulusoy, G Ozkan, M Alkanat, S Mungan… - American journal of …, 2013 - karger.com
Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …

[HTML][HTML] Curcumin-loaded nanoparticles protect against rhabdomyolysis-induced acute kidney injury

X Chen, J Sun, H Li, H Wang, Y Lin, Y Hu… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Rhabdomyolysis (RM) is a potentially life-threatening condition that
results from the breakdown of muscle and consequent release of toxic compounds into …