Early improvement and response to antidepressant medications in adults with major depressive disorder. Meta-analysis and study of a sample with treatment-resistant …
Background Initial improvement in the first weeks of antidepressant (AD) treatment is a
useful early predictor of complete AD response. We performed a meta-analysis of AD …
useful early predictor of complete AD response. We performed a meta-analysis of AD …
Early improvement as a resilience signal predicting later remission to antidepressant treatment in patients with major depressive disorder: systematic review and meta …
S Wagner, A Engel, J Engelmann, D Herzog… - Journal of psychiatric …, 2017 - Elsevier
Early improvement of depressive symptoms during the first two weeks of antidepressant
treatment has been discussed to be a resilience signal predicting a later positive treatment …
treatment has been discussed to be a resilience signal predicting a later positive treatment …
Predicting treatment response in major depressive disorder: the impact of early symptomatic improvement
Objective: Antidepressants (ADs) are the mainstay of treatment for major depressive
disorder (MDD). Despite their widespread usage, a consensus does not exist as to the …
disorder (MDD). Despite their widespread usage, a consensus does not exist as to the …
Does early improvement triggered by antidepressants predict response/remission?—Analysis of data from a naturalistic study on a large sample of inpatients with …
V Henkel, F Seemüller, M Obermeier, M Adli… - Journal of affective …, 2009 - Elsevier
BACKGROUND: Delayed onset of efficacy of antidepressants and a high proportion of
depressed patients being poor or non-responders to antidepressants are well known clinical …
depressed patients being poor or non-responders to antidepressants are well known clinical …
Is switching antidepressants following early nonresponse more beneficial in acute-phase treatment of depression?: a randomized open-label trial
S Nakajima, H Uchida, T Suzuki, K Watanabe… - Progress in Neuro …, 2011 - Elsevier
RATIONALE: Treatment guidelines for major depressive disorder (MDD) recommend a
continuous use of antidepressants for several weeks, while recent meta-analyses indicate …
continuous use of antidepressants for several weeks, while recent meta-analyses indicate …
Predictability of nonremitting depression after first 2 weeks of antidepressant treatment: a VAST-D trial report
PB Hicks, V Sevilimedu, GR Johnson… - … and clinical practice, 2019 - Am Psychiatric Assoc
Objective: In this secondary analysis of data from the Veterans Affairs Augmentation and
Switching Treatments for Improving Depression Outcomes (VAST-D) study, the authors …
Switching Treatments for Improving Depression Outcomes (VAST-D) study, the authors …
Predicting antidepressant response by monitoring early improvement of individual symptoms of depression: individual patient data meta-analysis
YA de Vries, AM Roest, EH Bos… - The British Journal of …, 2019 - cambridge.org
BackgroundImprovement in depression within the first 2 weeks of antidepressant treatment
predicts good outcomes, but non-improvers can still respond or remit, whereas improvers …
predicts good outcomes, but non-improvers can still respond or remit, whereas improvers …
The early improvement of depressive symptoms as a potential predictor of response to antidepressants in depressive patients who failed to respond to previous …
M Bares, T Novak, M Kopecek, P Stopkova, J Kozeny… - European …, 2012 - Elsevier
INTRODUCTION: Current studies suggest that improvement of depressive symptoms after 2
weeks of treatment could predict the subsequent response. The aim of our study was to …
weeks of treatment could predict the subsequent response. The aim of our study was to …
Improvement within 2 weeks and later treatment outcomes in patients with depressive disorders: the CRESCEND study
BACKGROUND: Although antidepressants are conventionally given for 4–6weeks before
deciding on response, several reports suggest that early improvement predicts later …
deciding on response, several reports suggest that early improvement predicts later …
Early switch strategy in patients with major depressive disorder: a double-blind, randomized study
I Romera, V Pérez, JM Menchón… - Journal of clinical …, 2012 - journals.lww.com
Objective Antidepressant switch is a commonly used strategy in the absence of an adequate
response, but optimum timing is not well established. We compared the efficacy of an early …
response, but optimum timing is not well established. We compared the efficacy of an early …