Prolactinoma

P Chanson, D Maiter - The pituitary, 2022 - Elsevier
Prolactinomas account for approximately 50% of all pituitary adenomas coming to medical
attention and are an important cause of hypogonadism and infertility. The ultimate goal of …

Dopamine agonist therapy in prolactinomas: when can treatment be discontinued?

A Klibanski - The Journal of Clinical Endocrinology & …, 2009 - academic.oup.com
The discovery and widespread use of dopamine agonists as an effective therapy for patients
with prolactinomas was a key therapeutic advance. However, despite the overall efficacy of …

Clinical management and outcome of 36 invasive prolactinomas treated with dopamine agonist

MS Yang, JW Hong, SK Lee, EJ Lee, SH Kim - Journal of neuro-oncology, 2011 - Springer
Abstract Treatment of invasive prolactinoma, which has several characteristics including
invasive growth into cavernous sinuses and formation of giant adenomas compressing …

Medical versus surgical treatment of prolactinomas: an analysis of treatment outcomes

MJ Rutkowski, MK Aghi - Expert Review of Endocrinology & …, 2018 - Taylor & Francis
Introduction: Prolactinomas are unique tumors that may go into both hormonal and
radiographic remission with dopamine agonist therapy or transsphenoidal surgery …

[HTML][HTML] Macroprolactinoma with secondary resistance to dopamine agonists: a case report and review of the literature

EL Tng, AED Teo, AT Aung - Journal of Medical Case Reports, 2023 - Springer
Background Resistance to dopamine agonists is not uncommonly seen in prolactinomas.
However, development of resistance to dopamine agonists after an initial period of robust …

[HTML][HTML] Diagnosis and management of prolactinomas: current challenges

S Petersenn, A Giustina - Pituitary, 2020 - Springer
Prolactinoma is the most frequent pituitary adenoma type, accounting for 40–66% in
epidemiological studies [1]. The estimated prevalence in various populations ranges from …

[HTML][HTML] Molecular pathways in prolactinomas: Translational and therapeutic implications

B Biagetti, R Simò - International Journal of Molecular Sciences, 2021 - mdpi.com
Prolactinoma has the highest incidence rate among patients with functional pituitary
tumours. Although mostly benign, there is a subgroup that can be aggressive. Some clinical …

[HTML][HTML] Case report: temozolomide treatment of refractory prolactinoma resistant to dopamine agonists

H Tang, Y Cheng, J Huang, J Li, B Zhang… - Frontiers in …, 2021 - frontiersin.org
Therapeutic agents for refractory prolactinomas that are resistant to dopamine agonists
(DAs) are troublesome, and surgery often only removes a large part of the tumor without …

Medical treatment of prolactinomas

A Colao, S Savastano - Nature Reviews Endocrinology, 2011 - nature.com
Prolactinomas, the most prevalent type of neuroendocrine disease, account for
approximately 40% of all pituitary adenomas. The most important clinical problems …

Management and outcomes of giant prolactinoma: a series of 71 patients

O ksana Hamidi, J Van Gompel, L Gruber, NE Kittah… - Endocrine Practice, 2019 - Elsevier
Objective: To describe outcomes of patients with giant prolactinoma (≥ 4 cm) and identify
predictors of therapeutic response. Methods: In this retrospective study, complete …