Diagnosis and drug therapy of prolactinoma

E Ciccarelli, F Camanni - Drugs, 1996 - Springer
A prolactin-secreting pituitary tumour is the most frequent cause of hyperprolactinaemia that
commonly occurs in clinical practice. Prolactinomas occur more frequently in women than in …

Giant prolactinomas larger than 60 mm in size: a cohort of massive and aggressive prolactin-secreting pituitary adenomas

I Shimon, E Sosa, V Mendoza, Y Greenman, A Tirosh… - Pituitary, 2016 - Springer
Objectives Prolactin (PRL)-secreting macroadenomas usually measure between 10 and 40
mm. Giant (adenoma size≥ 40 mm) PRL-tumors are not common, and larger prolactinomas …

Update on prolactinomas. Part 2: treatment and management strategies

A Wong, JA Eloy, WT Couldwell, JK Liu - Journal of Clinical neuroscience, 2015 - Elsevier
The authors present an update on the various treatment modalities and discuss
management strategies for prolactinomas. Prolactinomas are the most common type of …

The epidemiology, diagnosis and treatment of Prolactinomas: The old and the new

P Chanson, D Maiter - Best practice & research Clinical endocrinology & …, 2019 - Elsevier
Prevalence and incidence of prolactinomas are approximately 50 per 100,000 and 3–5 new
cases/100,000/year. The pathophysiological mechanism of hyperprolactinemia-induced …

[HTML][HTML] The mechanism and pathways of dopamine and dopamine agonists in prolactinomas

X Liu, C Tang, G Wen, C Zhong, J Yang… - Frontiers in …, 2019 - frontiersin.org
Dopamine agonists such as bromocriptine and cabergoline are the predominant treatment
drugs for prolactinoma by inhibiting prolactin secretion and shrinking tumor size. However …

Prolactinomas resistant to standard dopamine agonists respond to chronic cabergoline treatment

A Colao, A Di Sarno, F Sarnacchiaro… - The Journal of …, 1997 - academic.oup.com
Abstract Cabergoline (CAB), a new, potent, and long-lasting PRL-lowering agent, was
shown to be effective in tumoral hyperprolactinemia. The aim of this study was to investigate …

The combination of dopamine agonist treatment and surgery may be the best option in challenging prolactinoma cases: a single-centre experience

D Demir, AN Demir, C Sulu, G Zulfaliyeva… - World Neurosurgery, 2023 - Elsevier
Objective To investigate the initial and long-term remission rates, factors related to
remission, secondary treatments, and outcomes for patients with prolactinoma who …

[HTML][HTML] Predictors of dopamine agonist resistance in prolactinoma patients

E Vermeulen, J D'Haens, T Stadnik, D Unuane… - BMC Endocrine …, 2020 - Springer
Background Surgical resection of prolactinomas resistant to dopamine agonists is frequently
incomplete due to fibrotic changes of the tumour under pharmacological therapy. In order to …

[HTML][HTML] Are dopamine agonists still the first-choice treatment for prolactinoma in the era of endoscopy? A systematic review and meta-analysis

X Cai, J Zhu, J Yang, C Tang, Z Cong, C Ma - Chinese Neurosurgical …, 2022 - Springer
Background For prolactinoma patients, dopamine agonists (DAs) are indicated as the first-
line treatment and surgery is an adjunctive choice. However, with the development of …

Clinical management of prolactinomas

J Webster - Best Practice & Research Clinical Endocrinology & …, 1999 - Elsevier
Prolactinomas are benign, sporadic pituitary tumours that typically present with
amenorrhoea and galactorrhoea in women, and hypogonadism and space-occupying …