[HTML][HTML] ADAMs family in kidney physiology and pathology
H Zhu, J Wang, W Nie, I Armando, F Han - EBioMedicine, 2021 - thelancet.com
A disintegrin and metalloproteinases (ADAMs) family are proteolytic transmembrane
proteases that modulate diverse cell functions and coordinate intercellular communication …
proteases that modulate diverse cell functions and coordinate intercellular communication …
[HTML][HTML] Renal ADAM10 and 17: their physiological and medical meanings
T Kato, M Hagiyama, A Ito - Frontiers in cell and developmental …, 2018 - frontiersin.org
A disintegrin and metalloproteinases (ADAMs) are a Zn2+-dependent transmembrane and
secreted metalloprotease superfamily, so-called “molecular scissors,” and they consist of an …
secreted metalloprotease superfamily, so-called “molecular scissors,” and they consist of an …
[HTML][HTML] Ectodomain shedding by ADAM proteases as a central regulator in kidney physiology and disease
C Meyer-Schwesinger, L Seipold, P Saftig - Biochimica et Biophysica Acta …, 2022 - Elsevier
Besides its involvement in blood and bone physiology, the kidney's main function is to filter
substances and thereby regulate the electrolyte composition of body fluids, acid-base …
substances and thereby regulate the electrolyte composition of body fluids, acid-base …
ADAM17 upregulation in human renal disease: a role in modulating TGF-α availability?
WB Melenhorst, L Visser, A Timmer… - American Journal …, 2009 - journals.physiology.org
A disintegrin and metalloproteinase (ADAM) 17 sheds growth factors from the cell
membrane, including epidermal growth factor receptor (EGFR) ligand transforming growth …
membrane, including epidermal growth factor receptor (EGFR) ligand transforming growth …
[HTML][HTML] A disintegrin and metalloproteases (ADAMs) in cardiovascular, metabolic and inflammatory diseases: aspects for theranostic approaches
EPC van der Vorst, C Weber… - Thrombosis and …, 2018 - thieme-connect.com
A disintegrin and metalloproteases (ADAMs) are membrane-bound enzymes responsible for
the shedding or cleavage of various cell surface molecules, such as adhesion molecules …
the shedding or cleavage of various cell surface molecules, such as adhesion molecules …
Contribution of ADAM17 and related ADAMs in cardiovascular diseases
A disintegrin and metalloproteases (ADAMs) are key mediators of cell signaling by
ectodomain shedding of various growth factors, cytokines, receptors and adhesion …
ectodomain shedding of various growth factors, cytokines, receptors and adhesion …
[HTML][HTML] ADAM19 expression in human nephrogenesis and renal disease: associations with clinical and structural deterioration
W Melenhorst, MC van den Heuvel, A Timmer… - Kidney international, 2006 - Elsevier
ADAM19, an enzyme from the ADAM (ad isintegrin and metalloproteinase) family, is
involved in various cell–cell and cell–matrix interactions. It can cleave epidermal growth …
involved in various cell–cell and cell–matrix interactions. It can cleave epidermal growth …
Targeting ADAM10 in Renal Diseases
JN Wang, XJ Cao - Current Molecular Medicine, 2023 - ingentaconnect.com
ADAM10 is part of the ADAM superfamily containing cell surface proteins with special
structures and potential adhesion and protease domains. This paper provides a review of …
structures and potential adhesion and protease domains. This paper provides a review of …
[HTML][HTML] ADAM10 and ADAM17, Major Regulators of Chronic Kidney Disease Induced Atherosclerosis?
SL Maas, MMPC Donners… - International Journal of …, 2023 - mdpi.com
Chronic kidney disease (CKD) is a major health problem, affecting millions of people
worldwide, in particular hypertensive and diabetic patients. CKD patients suffer from …
worldwide, in particular hypertensive and diabetic patients. CKD patients suffer from …
Therapeutic benefits from targeting of ADAM family members
ML Moss, JW Bartsch - Biochemistry, 2004 - ACS Publications
Members of the ADAM (a disintegrin and metalloproteinase) family of proteolytic enzymes
are implicated in the processing of many single transmembrane-bound proteins ranging …
are implicated in the processing of many single transmembrane-bound proteins ranging …