As a consequence of improved management in acute coronary syndromes and improved
longevity of the population, the number of patients with heart failure is growing. The …

For many patients with terminal/advanced cardiac failure, heart transplantation is the most
effective, durable treatment option, and offers the best prospects for a high quality of life. The …

For the individual patient, further intervention is considered by comparing expected
outcomes with and without the intervention. Most experience with advanced heart failure has …

Patients with advanced heart failure have a dismal prognosis and poor quality of life. Heart
transplantation provides an effective treatment for a subset of these patients. This article …

With the introduction of cyclosporin A in the early 1980s, heart transplantation was
transformed from an experimental procedure into a successful therapeutic option for patients …

Heart transplantation is the only curative therapy for chronic heart failure, and it plays an
important role in the treatment of chronic heart failure with a survival rate of approximately …

The first human heart transplantation was performed by Christian Barnard in 1967. While the
technical aspect had been worked out, allograft rejection was a major limitation in the early …

Despite advances in medical and device therapy, the prognosis and quality of life of patients
with advanced heart failure (HF) remains poor. For a carefully selected group of these …

Although the burden of end-stage heart failure continues to increase, the number of
available organs for heart transplantation (HT) remains inadequate. The HT community has …

There has been significant progress in the field of heart transplantation over the last 45
years. The 1-yr survival rates following heart transplantation have improved from 30% in the …