A cross-sectional group study of the effects of aging on brain metabolism as measured with
18 F-FDG-PET was performed using several different partial volume correction (PVC) …

The primary method for measuring brain metabolism in humans is positron emission
tomography (PET) imaging using the tracer 18F-fluorodeoxyglucose (FDG). Standardized …

A new, computerized segmentation technique, in which magnetic resonance (MR) imaging
produces accurate volumetric measurements of brain and cerebrospinal fluid (CSF) without …

Principal component analysis (PCA) is a well‐known technique for reduction of
dimensionality of functional imaging data. PCA can be looked at as the projection of the …

Purpose The aim of this study was to investigate the effects of atrophy correction on the
results of 18 F-fluorodeoxyglucose positron emission tomography (FDG PET) in the context …

Measurements of cerebral metabolism in patients with Alzheimer's disease (AD) using PET
are artifactually depressed due to partial volume averaging of brain tissue activity with …

The use of positron emission tomography (PET) in quantitative fluorodeoxyglucose (FDG)
studies of aging and dementia has been limited by partial volume effects. A general method …

It remains a matter of controversy as to whether cerebral perfusion declines with healthy
aging. In vivo imaging with PET permits quantitative evaluation of brain physiology; …

With age, the brain undergoes both structural and functional alterations, probably resulting
in reported cognitive declines. Relatively few investigations have sought to identify those …

Due to the limited spatial resolution of positron emission tomography (PET), the accuracy of
quantitative measurements of regional metabolism or neuroreceptor concentration is …