Overexpression of growth-arrest-specific transcript 5 improved cisplatin sensitivity in hepatocellular carcinoma through sponging miR-222

P Zhao, X Cui, L Zhao, L Liu, D Wang - DNA and Cell Biology, 2020 - liebertpub.com
Long noncoding RNA growth-arrest-specific transcript 5 (GAS5) has been proved to play a
crucial role in cancer chemoresistance. However, the function of GAS5 and its underlying …

[HTML][HTML] Long non-coding RNA GAS5 antagonizes the chemoresistance of pancreatic cancer cells through down-regulation of miR-181c-5p

ZQ Gao, J Wang, DH Chen, XS Ma, W Yang… - Biomedicine & …, 2018 - Elsevier
Objective To explore the core mechanism of long non-coding RNA (lncRNA) growth arrest-
specific transcript 5 (GAS5) in the regulation of multidrug resistance of pancreatic cancer …

[HTML][HTML] LncRNA GAS5 enhances radiosensitivity of hepatocellular carcinoma and restricts tumor growth and metastasis by miR-144-5p/ATF2

C Yu, Y Liang, Y Jin, Q Li - American Journal of Translational …, 2021 - ncbi.nlm.nih.gov
Background: This study aimed to evaluate the biologic role of growth arrest-specific 5
(GAS5) in radiosensitivity of hepatocellular carcinoma (HCC). Methods: The levels of GAS5 …

[HTML][HTML] Long noncoding RNA GAS5 inhibits tumorigenesis and enhances radiosensitivity by suppressing miR-135b expression in non-small cell lung cancer

Y Xue, T Ni, Y Jiang, Y Li - Oncology research, 2017 - ncbi.nlm.nih.gov
Growth arrest-specific transcript 5 (GAS5) has been demonstrated to correlate with
clinicopathological characteristics and serve as a tumor suppressor in non-small cell lung …

[HTML][HTML] The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis

X Yang, L Meng, Y Zhong, F Hu, L Wang… - Aging (Albany NY …, 2021 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) are known to exert their effects to tumor progression. In
this study, the role of the lncRNA GAS5 (growth arrest specific 5) was confirmed in reducing …

lncRNA GAS5 reverses EMT and tumor stem cell-mediated gemcitabine resistance and metastasis by targeting miR-221/SOCS3 in pancreatic cancer

B Liu, S Wu, J Ma, S Yan, Z Xiao, L Wan… - … Therapy-Nucleic Acids, 2018 - cell.com
Dysregulated long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) mediating
chemotherapeutic drug effects and metastasis in pancreatic cancer (PC) are key reasons for …

Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by …

L Chang, C Li, T Lan, L Wu… - Molecular …, 2016 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer‑related mortality
worldwide. Recent studies have demonstrated that long non‑coding RNAs (lncRNAs) are …

Long non‑coding RNA GAS5 is critical for maintaining stemness and induces chemoresistance in cancer stem‑like cells derived from HCT116

X Zhou, D Xiao - Oncology Letters, 2020 - spandidos-publications.com
Long non-coding RNAs (lncRNAs) are recognized as critical regulators of self-renewal in
human cancer stem-like cells (CSCs), which are a subpopulation of cancer cells primarily …

Long noncoding RNA growth arrest‐specific 5 facilitates glioma cell sensitivity to cisplatin by suppressing excessive autophagy in an mTOR‐dependent manner

JF Huo, XB Chen - Journal of Cellular Biochemistry, 2019 - Wiley Online Library
Malignant glioma is a severe type of brain tumor with a grim prognosis. The occurrence of
resistance compromises the efficacy of chemotherapy for glioma. Long noncoding RNA …

GAS5 regulates RECK expression and inhibits invasion potential of HCC cells by sponging miR‐135b

L Yang, J Jiang - BioMed research international, 2019 - Wiley Online Library
Objectives. Long noncoding RNA (LncRNA) growth arrest‐specific 5 (GAS5) has been
characterized as a tumor suppressor in numerous kinds of human cancers. Its anticancer …