Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

KM Jørgensen, T Wassermann… - …, 2015 - microbiologyresearch.org
Pseudomonas aeruginosa is the dominant pathogen infecting the airways of cystic fibrosis
(CF) patients. During the intermittent colonization phase, P. aeruginosa resembles …

Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections

V Behrends, B Ryall, JEA Zlosnik… - Environmental …, 2013 - Wiley Online Library
Pseudomonas aeruginosa forms chronic infections in the lungs of cystic fibrosis (CF)
patients, and is the leading cause of morbidity and mortality in patients with CF …

Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient

J Rao, FH Damron, M Basler… - Frontiers in …, 2011 - frontiersin.org
Pseudomonas aeruginosa chronically infects the lungs of cystic fibrosis (CF) patients. The
conditions in the CF lung appear to select for P. aeruginosa with advantageous phenotypes …

A relationship between Pseudomonal growth behaviour and cystic fibrosis patient lung function identified in a metabolomic investigation

J Kozlowska, DW Rivett, LS Vermeer, MP Carroll… - Metabolomics, 2013 - Springer
Chronic polymicrobial lung infections in adult cystic fibrosis patients are typically dominated
by high levels of Pseudomonas aeruginosa. Determining the impact of P. aeruginosa growth …

Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

R La Rosa, HK Johansen, S Molin - Metabolites, 2019 - mdpi.com
Pseudomonas aeruginosa is one of the major causes of morbidity and mortality of cystic
fibrosis patients. During the infection, the bacteria colonize the nutritional rich lung mucus …

Genomic and functional characterization of longitudinal Pseudomonas aeruginosa isolates from young patients with cystic fibrosis

CE Chandler, CE Hofstaedter, TH Hazen… - Microbiology …, 2023 - Am Soc Microbiol
Individuals with cystic fibrosis (CF) suffer from frequent and recurring microbial airway
infections. The Gram-negative bacterium Pseudomonas aeruginosa is one of the most …

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

M Hogardt, J Heesemann - International Journal of Medical Microbiology, 2010 - Elsevier
The long-term persistance of P. aeruginosa in the cystic fibrosis (CF) lung is characterized
by the selection of a variety of genotypes and phenotypes that typically descend from one …

Genetically and Phenotypically Distinct Pseudomonas aeruginosa Cystic Fibrosis Isolates Share a Core Proteomic Signature

A Penesyan, SS Kumar, K Kamath, AM Shathili… - PloS one, 2015 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa is among the main colonizers of the
lungs of cystic fibrosis (CF) patients. We have isolated and sequenced several P …

Insights into the respiratory tract microbiota of patients with cystic fibrosis during early Pseudomonas aeruginosa colonization

M Keravec, J Mounier, E Prestat, S Vallet, JK Jansson… - Springerplus, 2015 - Springer
Pseudomonas aeruginosa plays a major role in cystic fibrosis (CF) progression. Therefore, it
is important to understand the initial steps of P. aeruginosa infection. The structure and …

Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis Lungs

J Klockgether, N Cramer, S Fischer… - American journal of …, 2018 - atsjournals.org
Chronic airway infections with Pseudomonas aeruginosa determine morbidity in most
individuals with cystic fibrosis (CF). P. aeruginosa may persist for decades in CF lungs …