Background The dysregulated mechanistic target of rapamycin complex 1 (mTORC1)
signaling plays a critical role in ferroptosis resistance and tumorigenesis. However, the …

Ferroptosis, a form of regulated cell death triggered by lipid hydroperoxide accumulation,
has an important role in a variety of diseases and pathological conditions, such as cancer …

Ferroptosis, a form of regulated necrosis driven by iron-dependent peroxidation of
phospholipids, is regulated by cellular metabolism, redox homeostasis, and various …

Previous studies have reported that mTORC2 promotes cell survival through
phosphorylating AKT and enhancing its activity. We reveal another mechanism by which …

Unfavorable clinical outcomes mean that cancer researchers must attempt to develop novel
therapeutic strategies to overcome therapeutic resistance in patients with HNSCC. Recently …

Targeting ferroptosis for cancer therapy has slowed because of an incomplete
understanding of ferroptosis mechanisms under specific pathological contexts such as …

Abstract Background N6-methyladenosine (m6A) has emerged as a significant regulator of
the progress of various cancers. However, its role in lung adenocarcinoma (LUAD) remains …

Ferroptosis, which is caused by iron‐dependent accumulation of lipid peroxides, is an
emerging form of regulated cell death and is considered a potential target for cancer …

Background MiRNA is a small molecule RNA that plays an important role in a variety of
physiological and pathological processes., and miR-34c-3p has been demonstrated to be …

Ferroptosis is a newly identified iron-dependent form of death that is becoming increasingly
recognized as a promising avenue for cancer therapy. N6-methyladenosine (m6A) is the …