To contribute to a better understanding of metalloenzymes, we studied ion selectivity,
complex formation tendencies and catalytic activities of linear and cyclic pseudopeptides. In …

Pseudotripeptide ligands with 4 different N-functionalized glycine residues were
qualitatively, semiquantitatively and quantitatively tested for their complexation of the …

Naturally occurring metalloproteins contain metal ions either to introduce a special reactivity
or to stabilize a peptide structure. Since the early 1990s, chemists have been trying to use …

To design a metalloprotein and metalloenzyme model, macrocyclic pseudopeptides
containing N, N′-ethylene-bridged-dipeptides were synthesized and their conformations …

Metal complexes with peptide or pseudopeptide type ligands can serve as good model
compounds for a deeper understanding of enzymatic catalysis, but ligands with a high …

To obtain more insight into catalytic mechanisms of metallo enzymes and specific metal
complexation by proteins we use linear and cyclic pseudopeptides as mimetics. Knowledge …

The sequence-to-function relationship of peptide-based catalysts remains a challenge, as
even subtle modifications at the sequence level can alternate their catalytic activity. A set of …

Peptides are multidentate chiral ligands capable of coordinating different metal ions.
Nowadays, they can be obtained with high yield and purity, thanks to the advances on …

The mutual relationship between peptides and metal ions enables metalloproteins to have
crucial roles in biological systems, including structural, sensing, electron transport, and …

Oligopeptides are involved in diverse biological activities, including neurotransmission and
antibiotic. Many natural‐occurring peptides and peptide‐ketide hybrids exhibit specific …