Considerable success has been made with many peptide antigen formulations and it
appears that peptide-based vaccines are emerging as the next generation of prophylactic …

The immune system is ignorant or even unresponsive to most foreign proteins that are
injected in a soluble, deaggregated form, but when injected together with an immune …

Considerable success has been made with many peptide antigen formulations, and peptide-
based vaccines are emerging as the next generation of prophylactic and remedial …

Targeted delivery of otherwise nonimmunogenic antigens to Toll-like receptors (TLRs)
expressed on dendritic cells (DCs) has proven to be an effective means of improving …

Toll-like receptors (TLRs) play prominent roles in initiating adaptive immune responses to
infection, but their roles in particular cell types in vivo are not established. Here we report the …

Effective therapeutic vaccines contain two primary constituents, antigen and adjuvant.
Adjuvants consisting of microbial pattern molecules play a central role in vaccination …

Dendritic cells (DCs) are required for the initiation of primary immune responses. The pattern
of Toll‐like receptor (TLR) expression on various subsets of these cells has been shown to …

Toll‐like receptor (TLR) signalling shapes dendritic cell (DC) responses by inducing co‐
stimulatory molecule up‐regulation and cytokine secretion while TLR regulatory proteins …

Abstract Background. Triggering Toll-like receptors (TLRs) on dendritic cells (DCs) induces
inflammatory cytokine production necessary for T helper type 1 immunity. The present study …

Dendritic cells are key components of successful immunological responses bridging innate
and adaptive defenses. In this study we wanted to know whether ligation of toll-like receptors …