[HTML][HTML] Natural killer cell dysfunction in hepatocellular carcinoma and NK cell-based immunotherapy
C Sun, H Sun, W Xiao, C Zhang, Z Tian - Acta Pharmacologica Sinica, 2015 - nature.com
The mechanisms linking hepatitis B virus (HBV) and hepatitis C virus (HCV) infection to
hepatocellular carcinoma (HCC) remain largely unknown. Natural killer (NK) cells account …
hepatocellular carcinoma (HCC) remain largely unknown. Natural killer (NK) cells account …
[HTML][HTML] The role of natural killer cells in liver inflammation
The liver is an important immunological site that can promote immune tolerance or
activation. Natural killer (NK) cells are a major immune subset within the liver, and therefore …
activation. Natural killer (NK) cells are a major immune subset within the liver, and therefore …
[HTML][HTML] Identification of a distinct NK-like hepatic T-cell population activated by NKG2C in a TCR-independent manner
Background & Aims The liver provides a unique niche of lymphocytes enriched with a large
proportion of innate-like T cells. However, the heterogeneity and functional characteristics of …
proportion of innate-like T cells. However, the heterogeneity and functional characteristics of …
Natural killer cells in liver disease and hepatocellular carcinoma and the NK cell‐based immunotherapy
P Liu, L Chen, H Zhang - Journal of Immunology Research, 2018 - Wiley Online Library
Nature killer (NK) cells play a critical role in host innate and adaptive immune defense
against viral infections and tumors. NK cells are enriched in liver hematopoietic cells with …
against viral infections and tumors. NK cells are enriched in liver hematopoietic cells with …
Activation and function of hepatic NK cells in hepatitis B infection: an underinvestigated innate immune response
Y Chen, H Wei, B Gao, Z Hu, S Zheng… - Journal of viral …, 2005 - Wiley Online Library
Natural killer (NK) cells are abundant in the normal liver, accounting for around one‐third of
intrahepatic lymphocytes and are important in the defence against hepatitis B virus (HBV) …
intrahepatic lymphocytes and are important in the defence against hepatitis B virus (HBV) …
Hepatitis C virus–infected cells downregulate NKp30 and inhibit ex vivo NK cell functions
KA Holder, SN Stapleton, ME Gallant… - The Journal of …, 2013 - journals.aai.org
Hepatitis C virus (HCV) successfully evades the immune system and establishes chronic
infection in∼ 80% of cases. Immune evasion may involve modulating NK cell functions …
infection in∼ 80% of cases. Immune evasion may involve modulating NK cell functions …
Hepatitis C virus infection downregulates the ligands of the activating receptor NKG2D
C Wen, X He, H Ma, N Hou, C Wei, T Song… - Cellular & molecular …, 2008 - nature.com
Natural killer (NK) cells are a major component of the host innate immune defense against
various pathogens. Several viruses, including hepatitis C virus (HCV), have developed …
various pathogens. Several viruses, including hepatitis C virus (HCV), have developed …
[PDF][PDF] Natural killer inhibitory receptor expression associated with treatment failure and interleukin‐28B genotype in patients with chronic hepatitis C
L Golden‐Mason, KM Bambha, L Cheng… - …, 2011 - Wiley Online Library
Natural killer (NK) cells constitute a first line of defense against viral infections; their function
is governed by the integration of signals from multiple activating and inhibitory surface …
is governed by the integration of signals from multiple activating and inhibitory surface …
Profiles of NK, NKT cell activation and cytokine production following vaccination against hepatitis B
B Albarran, L Goncalves, S Salmen, L Borges, H Fields… - Apmis, 2005 - Wiley Online Library
Human natural killer (NK) cells (CD56+ CD3−) represent crucial components of the innate
immune system especially against viral infections and because their activation can modulate …
immune system especially against viral infections and because their activation can modulate …
CMV drives clonal expansion of NKG2C+ NK cells expressing self‐specific KIRs in chronic hepatitis patients
Natural killer (NK) cells are affected by infection with human cytomegalovirus (HCMV)
manifested by increased expression of the HLA‐E binding activating receptor NKG2C. We …
manifested by increased expression of the HLA‐E binding activating receptor NKG2C. We …