[图书][B] Granulysin-induced apoptosis involves membrane disruption, mitochondrial damage, and caspase 9 activation
AA Kaspar - 1999 - search.proquest.com
Granulysin is an antimicrobial and cytolytic molecule expressed by cytotoxic T lymphocytes
(CTL) and natural killer (NK) cells. It is a member of the saposin-like protein (SAPLIP) family …
(CTL) and natural killer (NK) cells. It is a member of the saposin-like protein (SAPLIP) family …
A distinct pathway of cell-mediated apoptosis initiated by granulysin
AA Kaspar, S Okada, J Kumar, FR Poulain… - The Journal of …, 2001 - journals.aai.org
Granulysin is an antimicrobial and tumoricidal molecule expressed in granules of CTL and
NK cells. In this study, we show that granulysin damages cell membranes based upon …
NK cells. In this study, we show that granulysin damages cell membranes based upon …
[PDF][PDF] A Distinct Pathway of Cell-Mediated
AI by Granulysin - J Immunol, 2001 - academia.edu
Granulysin is an antimicrobial and tumoricidal molecule expressed in granules of CTL and
NK cells. In this study, we show that granulysin damages cell membranes based upon …
NK cells. In this study, we show that granulysin damages cell membranes based upon …
A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis
J Pardo, P Pérez-Galán, S Gamen, I Marzo… - The journal of …, 2001 - journals.aai.org
Granulysin is a cytolytic molecule released by CTL via granule-mediated exocytosis. In a
previous study we showed that granulysin induced apoptosis using both caspase-and …
previous study we showed that granulysin induced apoptosis using both caspase-and …
Granulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells
RV Saini, C Wilson, MW Finn, T Wang… - The Journal of …, 2011 - journals.aai.org
Granulysin is a human cytolytic molecule present in cytotoxic granules with perforin and
granzymes. Recombinant 9-kDa granulysin kills a variety of microbes, including bacteria …
granzymes. Recombinant 9-kDa granulysin kills a variety of microbes, including bacteria …
[PDF][PDF] Granulysin-Induced Apoptosis. I. Involvement
AMK Naval, A Anel - J Immunol, 1998 - academia.edu
Granulysin is a newly described cytolytic molecule released by CTL and NK cells via
granule-mediated exocytosis. It shares homology with saposin-like proteins, including NK …
granule-mediated exocytosis. It shares homology with saposin-like proteins, including NK …
Intracellularly expressed granulysin induced apoptosis in hepatoma cells and role of mitochondrial apoptotic pathway
Z Yi, Y Fu, G Jin, M Li, X Zhang, W Song - Cellular immunology, 2009 - Elsevier
Extracellularly added recombinant granulysin was reported to kill mammalian target cells.
The sites of actions and molecular mechanisms of granulysin in target cell killing, however …
The sites of actions and molecular mechanisms of granulysin in target cell killing, however …
Intracellular mediators of granulysin-induced cell death
S Okada, Q Li, JC Whitin, C Clayberger… - The Journal of …, 2003 - journals.aai.org
Granulysin, a molecule present in the granules of CTL and NK cells, is cytolytic against
microbes and tumors. Granulysin induces apoptosis of mammalian cells by damaging …
microbes and tumors. Granulysin induces apoptosis of mammalian cells by damaging …
Granulysin induces cell death with nuclear accumulation
Y Takamori, K Ogawa, K Nagata, S Takano… - Journal of Medical and …, 2005 - jstage.jst.go.jp
Exogenously added granulysin was reported to kill mammalian target cells. The sites of
actions and molecular mechanisms of granulysin in target cell killing, however, are presently …
actions and molecular mechanisms of granulysin in target cell killing, however, are presently …
Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways
S Gamen, DA Hanson, A Kaspar, J Naval… - The Journal of …, 1998 - journals.aai.org
Granulysin is a newly described cytolytic molecule released by CTL and NK cells via
granule-mediated exocytosis. It shares homology with saposin-like proteins, including NK …
granule-mediated exocytosis. It shares homology with saposin-like proteins, including NK …