Polymeric micro-and nanoparticles for immune modulation

E Ben-Akiva, SE Witte, RA Meyer, KR Rhodes… - Biomaterials …, 2019 - pubs.rsc.org
New advances in biomaterial-based approaches to modulate the immune system are being
applied to treat cancer, infectious diseases, and autoimmunity. Particulate systems are …

Engineering nano‐and microparticles to tune immunity

JJ Moon, B Huang, DJ Irvine - Advanced materials, 2012 - Wiley Online Library
The immune system can be a cure or cause of disease, fulfilling a protective role in attacking
cancer or pathogenic microbes but also causing tissue destruction in autoimmune disorders …

Micro and nanoparticle‐based delivery systems for vaccine immunotherapy: an immunological and materials perspective

J Leleux, K Roy - Advanced healthcare materials, 2013 - Wiley Online Library
The development and widespread application of vaccines has been one of the most
significant achievements of modern medicine. Vaccines have not only been instrumental in …

[HTML][HTML] Micro and nano material carriers for immunomodulation

E Bracho-Sanchez, CQ Xia, MJ Clare-Salzler… - American Journal of …, 2016 - Elsevier
Modulation of the immune system through the use of micro and nano carriers offers
opportunities in transplant tolerance, autoimmunity, infectious disease, and cancer. In …

[HTML][HTML] Engineering nanoparticles to overcome immunological barriers for enhanced drug delivery

T Malachowski, A Hassel - Engineered Regeneration, 2020 - Elsevier
Nanotechnology has recently gained traction in the medical field as a method of targeted
delivery and timed release of therapeutic drugs. As interest in this field grows, design …

Materials for immunotherapy

CW Shields IV, LLW Wang, MA Evans… - Advanced …, 2020 - Wiley Online Library
Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …

Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres

JS Lewis, C Roche, Y Zhang, TM Brusko… - Journal of Materials …, 2014 - pubs.rsc.org
Microparticulate systems are beginning to show promise for delivery of modulatory agents
for immunotherapeutic applications which modulate dendritic cell (DC) functions. Co …

Multivalent nanomaterials: learning from vaccines and progressing to antigen-specific immunotherapies

BL Hartwell, L Antunez, BP Sullivan, S Thati… - Journal of …, 2015 - Elsevier
Continued development of multivalent nanomaterials has provided opportunities for the
advancement of antigen-specific immunotherapies. New insights emerge when considering …

[HTML][HTML] Advances in engineered polymer nanoparticle tracking platforms towards cancer immunotherapy—Current status and future perspectives

R Thangam, KD Patel, H Kang, R Paulmurugan - Vaccines, 2021 - mdpi.com
Engineering polymeric nanoparticles for their shape, size, surface chemistry, and
functionalization using various targeting molecules has shown improved biomedical …

Engineered multifunctional nano‐and biological materials for cancer immunotherapy

A Brouillard, N Deshpande… - Advanced Healthcare …, 2021 - Wiley Online Library
Cancer immunotherapy is set to emerge as the future of cancer therapy. However, recent
immunotherapy trials in different cancers have yielded sub‐optimal results, with durable …