Understanding the regulation of cardiac fibrosis is critical for controlling adverse cardiac
remodeling during heart failure. Previously we identified miR-378 as a cardiomyocyte …

Understanding the regulation of cardiomyocyte growth is crucial for the management of
adverse ventricular remodeling and heart failure. MicroRNA-378 (miR-378) is a newly …

Cardiac fibrosis after myocardial infarction (MI) has been identified as a key factor in the
development of heart failure. Although dysregulation of microRNA (miRNA) is involved in …

Background An increasing number of studies have demonstrated the critical role of
microRNAs in the pathogenesis of cardiac hypertrophy and dysfunction. This study …

Background/Aims: Deregulated myocardial fibrosis is associated with a wide spectrum of
cardiac conditions, being considered one of the major causes for heart disease. Our study …

Recent studies have begun to reveal critical roles of microRNAs (miRNAs) in the
pathogenesis of cardiac hypertrophy and dysfunction. In this study, we tested whether a …

Cardiac hypertrophy is the response of the heart to a variety of hypertrophic stimuli; this
condition progresses to heart failure and sudden death. MicroRNAs (miRs) are a family of …

Rationale: In response to mechanical and pathological stress, adult mammalian hearts often
undergo mal-remodeling, a process commonly characterized as pathological hypertrophy …

Background/Aims: Cardiac fibrosis after myocardial infarction (MI) has been identified as a
key factor in the development of heart failure, but the mechanisms undelying cardiac fibrosis …

Cardiac hypertrophy, which is characterized by an increase in cell size and reactivation of
fetal genes, occurs as an adaptive response to diverse forms of stress and often results in …