Purpose Next-generation sequencing technology like MPS has recently been introduced to
perform comprehensive chromosome screening on human trophectoderm samples for …

Preimplantation genetic diagnosis and screening are widely accepted for chromosomal
abnormality identification to avoid transferring embryos with genetic defects. Massively …

Objective To add evidence that massive parallel sequencing (MPS) is a valuable substitute
for array comparative genomic hybridization (arrayCGH) with a resolution that is more …

Objective To determine how often the results of a single trophectoderm (TE) biopsy tested by
PGTseq, a targeted next-generation sequencing preimplantation genetic testing for …

Massively parallel genome sequencing, also known as next-generation sequencing (NGS),
is the latest approach for preimplantation genetic diagnosis. The purpose of this study was to …

Fluorescent in-situ hybridization (FISH) for preimplantation genetic diagnosis (PGD) of
structural chromosome abnormalities has limitations, including carrier testing, inconclusive …

STUDY QUESTION Can simultaneous comprehensive chromosome screening (CCS) and
gene expression analysis be performed on the same biopsy of preimplantation human …

Objective To establish the value of array comparative genomic hybridization (CGH) for
preimplantation genetic diagnosis (PGD) in embryos of translocation carriers in combination …

Background Aneuploidy is a leading cause of repeat implantation failure and recurrent
miscarriages. Preimplantation genetic screening (PGS) enables the assessment of the …

Shallow whole genome sequencing has recently been introduced for genome-wide
detection of chromosomal copy number alterations (CNAs) in preimplantation genetic …