Periosteum-mimicking tissue-engineered composite for treating periosteum damage in critical-sized bone defects

S Gupta, AK Teotia, I Qayoom, PA Shiekh… - …, 2021 - ACS Publications
The periosteum is an indispensable part of the bone that nourishes the cortical bone and
acts as a repertoire of osteoprogenitor cells. Periosteal damage as a result of traumatic …

Tissue engineered periosteum: Fabrication of a gelatin basedtrilayer composite scaffold with biomimetic properties for enhanced bone healing

S Tariq, SA Shah, F Hameed, Z Mutahir… - International Journal of …, 2024 - Elsevier
The periosteum, a vascularized tissue membrane, is essential in bone regeneration
following fractures and bone loss due to some other reasons, yet there exist several …

Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction

T Wang, Y Zhai, M Nuzzo, X Yang, Y Yang, X Zhang - Biomaterials, 2018 - Elsevier
Periosteum plays an indispensable role in bone repair and reconstruction. To recapitulate
the remarkable regenerative capacity of periosteum, a biomimetic tissue-engineered …

Self-adhesive hydrogel biomimetic periosteum to promote critical-size bone defect repair via synergistic osteogenesis and angiogenesis

Z Yang, Z Yang, L Ding, P Zhang, C Liu… - … applied materials & …, 2022 - ACS Publications
The periosteum plays an important role in the regeneration of critical-size bone defects, with
functions of recruiting multiple cells, accelerating vascular network reconstruction, and …

Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration

G Yang, H Liu, Y Cui, J Li, X Zhou, N Wang, F Wu, Y Li… - Biomaterials, 2021 - Elsevier
Periosteum plays a pivotal role in vascularization, ossification and remodeling during the
healing process of bone injury. However, there are few studies focused on the construction …

An enhanced periosteum structure/function dual mimicking membrane for in-situ restorations of periosteum and bone

L Laijun, Z Yu, L Chaojing, M Jifu, W Fujun, W Lu - Biofabrication, 2021 - iopscience.iop.org
Periosteum plays a pivotal role in bone formation and reconstruction. The ideal repair
process for critical-size bone defects with periosteum damage is to induce regeneration of …

Hierarchical micro/nanofibrous membranes of sustained releasing VEGF for periosteal regeneration

L Wu, Y Gu, L Liu, J Tang, J Mao, K Xi, Z Jiang, Y Zhou… - Biomaterials, 2020 - Elsevier
The periosteum plays a vital role in both development and injury healing process of bone.
However, few researches have focused on artificial periosteum, which was also limited by …

[HTML][HTML] A hierarchical biomimetic periosteum combined immunomodulatory and osteogenic functions for bone regeneration

X Li, S Yang, S Wang, S Li, H Jiang, W Hu, P Liu… - Composites Part B …, 2022 - Elsevier
The periosteum plays an indispensable role in immunomodulation and osteogenesis during
bone regeneration. The natural periosteum has a hierarchical structure, in which the outer …

Biomimetic periosteum-bone substitute composed of preosteoblast-derived matrix and hydrogel for large segmental bone defect repair

Y Yu, Y Wang, W Zhang, H Wang, J Li, L Pan, F Han… - Acta biomaterialia, 2020 - Elsevier
Repairing large segmental bone defects above a critical size remains challenging with high
risk of delayed union or even non-union. From the perspective of bone development and …

Hamburger-like biomimetic nutrient periosteum with osteoimmunomodulation, angio-/osteo-genesis capacity promoted critical-size bone defect repair

S Hao, D Zhou, F Wang, G Li, A Deng, X Ren… - Chemical Engineering …, 2024 - Elsevier
The periosteum is pivotal in bone repair, serving as a key facilitator for new bone formation
through its osteoimmunomodulation and neovascularization. However, autologous …