Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos

M Karimi, H Mirshekari, SMM Basri, S Bahrami… - Advanced drug delivery …, 2016 - Elsevier
The main goal of drug delivery systems is to target therapeutic cargoes to desired cells and
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …

Drug delivery vectors based on filamentous bacteriophages and phage-mimetic nanoparticles

Z Ju, W Sun - Drug Delivery, 2017 - Taylor & Francis
With the development of nanomedicine, a mass of nanocarriers have been exploited and
utilized for targeted drug delivery, including liposomes, polymers, nanoparticles, viruses …

Bacteriophages as therapeutic and diagnostic vehicles in cancer

V Foglizzo, S Marchiò - Pharmaceuticals, 2021 - mdpi.com
Evolution of nanomedicine is the re-design of synthetic and biological carriers to implement
novel theranostic platforms. In recent years, bacteriophage research favors this process …

Formulation strategies for bacteriophages to target intracellular bacterial pathogens

W Yan, P Banerjee, M Xu, S Mukhopadhyay… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteriophages (Phages) are antibacterial viruses that are unaffected by antibiotic drug
resistance. Many Phase I and Phase II phage therapy clinical trials have shown acceptable …

In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines

L Vaks, I Benhar - Journal of nanobiotechnology, 2011 - Springer
Background Targeted drug-carrying phage nanomedicines are a new class of
nanomedicines that combines biological and chemical components into a modular …

[HTML][HTML] Immunocompatibility of bacteriophages as nanomedicines

T Kaur, N Nafissi, O Wasfi, K Sheldon… - Journal of …, 2012 - hindawi.com
Bacteriophage-based medical research provides the opportunity to develop targeted
nanomedicines with heightened efficiency and safety profiles. Filamentous phages also can …

Killing cancer cells by targeted drug-carrying phage nanomedicines

H Bar, I Yacoby, I Benhar - BMC biotechnology, 2008 - Springer
Background Systemic administration of chemotherapeutic agents, in addition to its anti-
tumor benefits, results in indiscriminate drug distribution and severe toxicity. This …

[HTML][HTML] Nanotechnology based approaches in phage therapy: overcoming the pharmacological barriers

S Kaur, A Kumari, A Kumari Negi, V Galav… - Frontiers in …, 2021 - frontiersin.org
With the emergence and spread of global antibiotic resistance and the need for searching
safer alternatives, there has been resurgence in exploring the use of bacteriophages in the …

Paving the way for phage therapy using novel drug delivery approaches

T Briot, C Kolenda, T Ferry, M Medina, F Laurent… - Journal of Controlled …, 2022 - Elsevier
Bacterial resistance against antibiotics is an emergent medical issue. The development of
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …

Encapsulation and delivery of therapeutic phages

B Loh, VS Gondil, P Manohar, FM Khan… - Applied and …, 2021 - Am Soc Microbiol
Delivery of therapeutic compounds to the site of action is crucial. While many chemical
substances such as beta-lactam antibiotics can reach therapeutic levels in most parts …