Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos
The main goal of drug delivery systems is to target therapeutic cargoes to desired cells and
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …
Drug delivery vectors based on filamentous bacteriophages and phage-mimetic nanoparticles
Z Ju, W Sun - Drug Delivery, 2017 - Taylor & Francis
With the development of nanomedicine, a mass of nanocarriers have been exploited and
utilized for targeted drug delivery, including liposomes, polymers, nanoparticles, viruses …
utilized for targeted drug delivery, including liposomes, polymers, nanoparticles, viruses …
Bacteriophages as therapeutic and diagnostic vehicles in cancer
V Foglizzo, S Marchiò - Pharmaceuticals, 2021 - mdpi.com
Evolution of nanomedicine is the re-design of synthetic and biological carriers to implement
novel theranostic platforms. In recent years, bacteriophage research favors this process …
novel theranostic platforms. In recent years, bacteriophage research favors this process …
Formulation strategies for bacteriophages to target intracellular bacterial pathogens
W Yan, P Banerjee, M Xu, S Mukhopadhyay… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteriophages (Phages) are antibacterial viruses that are unaffected by antibiotic drug
resistance. Many Phase I and Phase II phage therapy clinical trials have shown acceptable …
resistance. Many Phase I and Phase II phage therapy clinical trials have shown acceptable …
In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines
L Vaks, I Benhar - Journal of nanobiotechnology, 2011 - Springer
Background Targeted drug-carrying phage nanomedicines are a new class of
nanomedicines that combines biological and chemical components into a modular …
nanomedicines that combines biological and chemical components into a modular …
[HTML][HTML] Immunocompatibility of bacteriophages as nanomedicines
T Kaur, N Nafissi, O Wasfi, K Sheldon… - Journal of …, 2012 - hindawi.com
Bacteriophage-based medical research provides the opportunity to develop targeted
nanomedicines with heightened efficiency and safety profiles. Filamentous phages also can …
nanomedicines with heightened efficiency and safety profiles. Filamentous phages also can …
Killing cancer cells by targeted drug-carrying phage nanomedicines
Background Systemic administration of chemotherapeutic agents, in addition to its anti-
tumor benefits, results in indiscriminate drug distribution and severe toxicity. This …
tumor benefits, results in indiscriminate drug distribution and severe toxicity. This …
[HTML][HTML] Nanotechnology based approaches in phage therapy: overcoming the pharmacological barriers
With the emergence and spread of global antibiotic resistance and the need for searching
safer alternatives, there has been resurgence in exploring the use of bacteriophages in the …
safer alternatives, there has been resurgence in exploring the use of bacteriophages in the …
Paving the way for phage therapy using novel drug delivery approaches
T Briot, C Kolenda, T Ferry, M Medina, F Laurent… - Journal of Controlled …, 2022 - Elsevier
Bacterial resistance against antibiotics is an emergent medical issue. The development of
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …
Encapsulation and delivery of therapeutic phages
Delivery of therapeutic compounds to the site of action is crucial. While many chemical
substances such as beta-lactam antibiotics can reach therapeutic levels in most parts …
substances such as beta-lactam antibiotics can reach therapeutic levels in most parts …