More than half of women take medications during breastfeeding, predisposing their infants
to medication exposure via breast milk. As a result, adverse drug reactions may emerge in …

Assessing the safety of breast feeding during maternal drug therapy is an individualised risk:
benefit analysis. An infant's exposure depends on drug transfer into milk, daily milk intake …

Knowledge of pharmacokinetics and the use of a mechanistic-based approach can improve
our ability to predict the effects of pregnancy for medications when data are limited. Despite …

There are many benefits of breast-feeding both for the infant and for the mother. Nursing
mothers who are also taking medications or exposed to environmental hazards may be …

Breastfeeding is the optimal form of infant feeding for the first months of an infant's life, and
the majority of healthy women initiate breastfeeding after the birth of their infant. However …

The trend globally for mothers to breastfeed has highlighted the need for information on drug
transfer into breast milk and the extent to which the suckling neonate may be exposed and …

Breastfeeding has positive health consequences for both the breastfed infant and the
nursing mother. 1, 2 Although information on drug use during lactation is available through …

Drugs ingested by a lactating mother would be expected to appear in human milk to some
extent and be ingested by a breast-feeding infant. Drugs pass from maternal plasma into …

Section 1 describes the benefits of breastfeeding to both mother and infant as well as the
potential risks to the infant from maternal drug use. The extent of adverse drug-related …

1. We present a novel index for expressing the exposure of the infant to drugs in breast milk,
which unifies two independent factors: a pharmacokinetic parameter, drug clearance, and a …