Microbiota alterations and their association with oncogenomic changes in pancreatic cancer patients

H Sammallahti, A Kokkola, S Rezasoltani… - International Journal of …, 2021 - mdpi.com
Pancreatic cancer (PC) is an aggressive disease with a high mortality and poor prognosis.
The human microbiome is a key factor in many malignancies, having the ability to alter host …

The role of microbiota in pancreatic cancer

V Papa, T Schepis, G Coppola, MF Chiappetta… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer is a devasting disease that has unfortunately proven
very difficult to treat. Exploring new therapeutic options and getting an early diagnosis is …

A comprehensive review of the multifaceted role of the microbiota in human pancreatic carcinoma

G Pandya, A Kirtonia, A Singh, A Goel… - Seminars in cancer …, 2022 - Elsevier
Pancreatic carcinoma is associated with one of the worst clinical outcomes throughout the
globe because of its aggressive, metastatic, and drug-resistant nature. During the past …

Association of the microbiota and pancreatic cancer: opportunities and limitations

Z Chen, S Zhang, S Dong, H Xu, W Zhou - Frontiers in Immunology, 2022 - frontiersin.org
The human body is thoroughly colonized by a wide variety of microorganisms, termed
microbiota. Pancreatic cancer, one of the most aggressive forms of cancer, is no exception …

Microbiota regulates pancreatic Cancer carcinogenesis through altered immune response

Y Chai, Z Huang, X Shen, T Lin, Y Zhang, X Feng… - Microorganisms, 2023 - mdpi.com
The microbiota is present in many parts of the human body and plays essential roles. The
most typical case is the occurrence and development of cancer. Pancreatic cancer (PC), one …

Potential roles of the gut microbiota in pancreatic carcinogenesis and therapeutics

Q Yang, J Zhang, Y Zhu - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
The intestinal microenvironment is composed of normal gut microbiota and the environment
in which it lives. The largest microecosystem in the human body is the gut microbiota, which …

Gut microbiota: its potential roles in pancreatic cancer

Q Li, M Jin, Y Liu, L Jin - Frontiers in cellular and infection …, 2020 - frontiersin.org
Pancreatic cancer is considered a lethal disease with a low survival rate due to its late-stage
diagnosis, few opportunities for resection and lack of effective therapeutic strategies …

Pancreatic cancer meets human microbiota: close encounters of the third kind

T Arsenijevic, R Nicolle, C Bouchart, N D'Haene… - Cancers, 2021 - mdpi.com
Simple Summary The microorganisms colonizing the epithelial surfaces of the human body,
called microbiota, have been shown to influence the initiation, progression and response to …

Microbiota in the natural history of pancreatic cancer: From predisposition to therapy

C Binda, G Gibiino, M Sbrancia, C Coluccio, M Cazzato… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer is still burdened with a severe prognosis, despite
advances in the diagnosis and surgical management of this disease. The gut microbiome is …

[HTML][HTML] Pancreatic cancer, gut microbiota, and therapeutic efficacy

X Zhang, Q Liu, Q Liao, Y Zhao - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Pancreatic cancer remains one of the leading causes of cancer-related death worldwide and
has a poor prognosis. Current treatment relies on surgical resection and adjuvant therapies …