Exercise as a polypill for chronic diseases

H Pareja-Galeano, N Garatachea, A Lucia - Progress in molecular biology …, 2015 - Elsevier
Exercise may be described as a polypill to prevent and/or treat almost every chronic
disease, with obvious benefits such as its low cost and practical lack of adverse effects …

Effects of exercise and diet on chronic disease

CK Roberts, RJ Barnard - Journal of applied physiology, 2005 - journals.physiology.org
Currently, modern chronic diseases, including cardiovascular diseases, Type 2 diabetes,
metabolic syndrome, and cancer, are the leading killers in Westernized society and are …

The physiology of optimizing health with a focus on exercise as medicine

BK Pedersen - Annual review of physiology, 2019 - annualreviews.org
Physical inactivity is one of the leading health problems in the world. Strong epidemiological
and clinical evidence demonstrates that exercise decreases the risk of more than 35 …

Waging war on modern chronic diseases: primary prevention through exercise biology

FW Booth, SE Gordon, CJ Carlson… - Journal of applied …, 2000 - journals.physiology.org
In this review, we develop a blueprint for exercise biology research in the new millennium.
The first part of our plan provides statistics to support the contention that there has been an …

Exercise and health: historical perspectives and new insights

M Hargreaves - Journal of Applied Physiology, 2021 - journals.physiology.org
Since ancient times, the health benefits of regular physical activity/exercise have been
recognized and the classic studies of Morris and Paffenbarger provided the epidemiological …

Exercise acts as a drug; the pharmacological benefits of exercise

J Vina, F Sanchis‐Gomar… - British journal of …, 2012 - Wiley Online Library
The beneficial effects of regular exercise for the promotion of health and cure of diseases
have been clearly shown. In this review, we would like to postulate the idea that exercise …

Molecular mechanisms of exercise and healthspan

Y Guan, Z Yan - Cells, 2022 - mdpi.com
Healthspan is the period of our life without major debilitating diseases. In the modern world
where unhealthy lifestyle choices and chronic diseases taper the healthspan, which lead to …

Health benefits of exercise

GN Ruegsegger, FW Booth - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Overwhelming evidence exists that lifelong exercise is associated with a longer health span,
delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the …

[HTML][HTML] Physical activity and aging: a life-long story

OL Charansonney - Discovery medicine, 2011 - discoverymedicine.com
The benefits of physical activity in preventing premature mortality have been established by
a large set of epidemiological studies. These benefits have been shown both in middle-aged …

Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …