Induction of hepatic nitric oxide synthase(NOS) by tumor necrosis factor-a(TNFa), interleukin-
1 f3 (IL-i p), interferon-y (IFN'y), interleukin-6(IL-6), and lipopolysaccharide was assessed as …

We have previously proposed that cytokine-stimulated nitric oxide (NO) production is
responsible for reversible myocardial depression in sepsis, trauma and ischemia. NO …

Nitric oxide biosynthesis in cardiac muscle leads to a decreased oxygen consumption and
lower ATP synthesis. It is suggested that this effect of nitric oxide is mainly due to the …

Immunohistochemistry shows that skeletal muscle fibers express endothelial-type (ec)-NOS
in a heterogeneous pattern distinct from that of neuronal (nc)-NOS. Analysis of adjacent …

Nitric oxide (NO) inhibits the mitochondrial respiratory chain, resulting in inhibition of ATP
production, increased oxidant production and increased susceptibility to cell death. NO …

One of the many routes proposed for the cellular inactivation of endogenous nitric oxide
(NO) is by the cytochrome c oxidase of the mitochondrial respiratory chain. We have studied …

Our objective was to determine the precise role of endothelial nitric oxide synthase (eNOS)
as a modulator of cardiac O2 consumption and to further examine the role of nitric oxide …

We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative
phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen …

Arginase exists in two isoforms. Liver-type arginase (arginase I) is expressed almost
exclusively in the liver and catalyzes the last step of urea synthesis, whereas the nonhepatic …

Mitochondrial biochemistry is complex, expanding from oxygen consumption, oxidative
phosphorylation, lipid catabolism, heme biosynthesis, to apoptosis, calcium homeostasis …