In vitro labeling of hydroxyapatite minerals by an engineered protein

E Yuca, AY Karatas, UOS Seker… - Biotechnology and …, 2011 - Wiley Online Library
Biological and biomimetic synthesis of inorganics have been a major focus in hard tissue
engineering as well as in green processing of advanced materials. Among the minerals …

Direct transformation from amorphous to crystalline calcium phosphate facilitated by motif-programmed artificial proteins

T Tsuji, K Onuma, A Yamamoto… - Proceedings of the …, 2008 - National Acad Sciences
An animal's hard tissue is mainly composed of crystalline calcium phosphate. In vitro, small
changes in the reaction conditions affect the species of calcium phosphate formed, whereas …

Identification of a highly specific hydroxyapatite‐binding peptide using phage display

MD Roy, SK Stanley, EJ Amis, ML Becker - Advanced Materials, 2008 - Wiley Online Library
A peptide sequence SVSVGMKPSPRP that selectively recognizes hydroxyapatite (HA) is
identified by using a phage display approach. The engineered sequence exhibits chemical …

Biomineralization of calcium phosphate crystals controlled by protein–protein interactions

E Duman, E Şahin Kehribar, RE Ahan… - ACS Biomaterials …, 2019 - ACS Publications
Hydroxyapatite (HAP) is the major biomineral of bone. Despite the large number of studies
addressing HAP formation, a fundamental understanding of the critical roles of HAP-forming …

Quantification of the binding affinity of a specific hydroxyapatite binding peptide

MC Weiger, JJ Park, MD Roy, CM Stafford, A Karim… - Biomaterials, 2010 - Elsevier
The genesis of bone and teeth involves highly coordinated processes, which involve
multiple cell types and proteins that direct the nucleation and crystallization of inorganic …

Effect of proteins on the synthesis and assembly of calcium phosphate nanomaterials

Y Cai, J Yao - Nanoscale, 2010 - pubs.rsc.org
Recent developments on biomineralization and biomaterials have demonstrated that
proteins play an important role in the formation of biominerals in the body, which induce or …

Selection and identification of a novel bone-targeting peptide for biomedical imaging of bone

J Bang, H Park, J Yoo, D Lee, WI Choi, JH Lee… - Scientific reports, 2020 - nature.com
The global burden of bone-related diseases is increasing in the aging society; thus,
improved bone targeted imaging for their early identification and treatment are needed. In …

Inhibition of osteoblast mineralization by phosphorylated phage-derived apatite-specific peptide

J Ramaswamy, HK Nam, H Ramaraju, NE Hatch… - Biomaterials, 2015 - Elsevier
Functionalization of biomaterials with material-and cell-specific peptide sequences allows
for better control of their surface properties and communication with the surrounding …

Phosphorylation-dependent mineral-type specificity for apatite-binding peptide sequences

WN Addison, SJ Miller, J Ramaswamy, A Mansouri… - Biomaterials, 2010 - Elsevier
Apatite-binding peptides discovered by phage display provide an alternative design method
for creating functional biomaterials for bone and tooth tissue repair. A limitation of this …

Evolutionary screening of collagen-like peptides that nucleate hydroxyapatite crystals

WJ Chung, KY Kwon, J Song, SW Lee - Langmuir, 2011 - ACS Publications
The biogenesis of inorganic/organic composite materials such as bone typically involves the
process of templated mineralization. Biomimetic synthesis of bone-like materials therefore …